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Titolo:
Minireview: genomic organization of the human ER alpha gene promoter region
Autore:
Kos, M; Reid, G; Denger, S; Gannon, F;
Indirizzi:
European Mol Biol Lab, D-69117 Heidelberg, Germany European Mol Biol Lab Heidelberg Germany D-69117 117 Heidelberg, Germany
Titolo Testata:
MOLECULAR ENDOCRINOLOGY
fascicolo: 12, volume: 15, anno: 2001,
pagine: 2057 - 2063
SICI:
0888-8809(200112)15:12<2057:MGOOTH>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESTROGEN-RECEPTOR GENE; THYROID-HORMONE RECEPTOR; MESSENGER-RNA ISOFORMS; BREAST-CANCER; START SITES; IDENTIFICATION; EXPRESSION; RAT; TRANSCRIPTS; VARIANTS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Kos, M European Mol Biol Lab, Meyerhofstr 1, D-69117 Heidelberg, Germany European Mol Biol Lab Meyerhofstr 1 Heidelberg Germany D-69117 any
Citazione:
M. Kos et al., "Minireview: genomic organization of the human ER alpha gene promoter region", MOL ENDOCR, 15(12), 2001, pp. 2057-2063

Abstract

The ER alpha gene has been intensively studied for more than a decade. During this long time, multiple promoters used in ER alpha expression have been discovered in several species. Although an already large body of literature describing various aspects of the regulation of ER alpha expression and utilization of different promoters is constantly growing, the inconsistent terminology used by individual authors makes the interpretation and comparison of data very difficult. Furthermore, completion of the human genome project now allows all known human ER alpha promoters to be placed on a physical map. This review describes promoters used in the generation of ER alpha transcripts in human and in other species and suggests a consistent nomenclature. The possible role of multiple promoters in the differential expression of ER alpha in tissues and during development is also discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 01:41:35