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Titolo:
Asymmetric synthesis of beta-amino acid scaffolds
Autore:
Bull, SD; Davies, SG; Smith, AD;
Indirizzi:
Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England Univ Oxford Oxford England OX1 3QY Perrins Lab, Oxford OX1 3QY, England
Titolo Testata:
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
fascicolo: 22, , anno: 2001,
pagine: 2931 - 2938
SICI:
1472-7781(2001):22<2931:ASOBAS>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SECONDARY STRUCTURES; MICHAEL ADDITIONS; DERIVATIVES; DIHYDROXYLATION; STRATEGY; PEPTIDES; TEMPLATE; ESTERS; SHAPE; UNITS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Davies, SG Univ Oxford, Dyson Perrins Lab, S Parks Rd, Oxford OX1 3QY, England Univ Oxford S Parks Rd Oxford England OX1 3QY OX1 3QY, England
Citazione:
S.D. Bull et al., "Asymmetric synthesis of beta-amino acid scaffolds", J CHEM S P1, (22), 2001, pp. 2931-2938

Abstract

Addition of two or three equivalents of lithium (S)-N-benzyl-N-alpha -methylbenzylamide to conjugate acceptors containing two or three alpha,beta -unsaturated ester fragments respectively and subsequent hydrogenolytic deprotection a ord homochiral bis- or tris-beta -amino esters containing two or three new stereogenic centres in high de and ee.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 02:19:40