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Titolo:
Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis
Autore:
Kalantar-Zadeh, K; Kopple, JD; Block, G; Humphreys, MH;
Indirizzi:
Univ Calif San Francisco, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA San Francisco Gen Hosp, Div Nephrol, San Francisco, CA 94110 USA San Francisco Gen Hosp San Francisco CA USA 94110 Francisco, CA 94110 USA Univ Calif Los Angeles, Harbor Med Ctr, Div Nephrol, Torrance, CA 90509 USA Univ Calif Los Angeles Torrance CA USA 90509 hrol, Torrance, CA 90509 USA Univ Calif Berkeley, Sch Publ Hlth, Berkeley, CA 94720 USA Univ Calif Berkeley Berkeley CA USA 94720 bl Hlth, Berkeley, CA 94720 USA
Titolo Testata:
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
fascicolo: 12, volume: 12, anno: 2001,
pagine: 2797 - 2806
SICI:
1046-6673(200112)12:12<2797:AASQOL>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
STAGE RENAL-DISEASE; SUBJECTIVE GLOBAL ASSESSMENT; FUNCTIONAL STATUS; DIALYSIS PATIENTS; OF-LIFE; MAINTENANCE HEMODIALYSIS; PREDICT MORTALITY; HEALTH-STATUS; DEPRESSION; SURVIVAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Kalantar-Zadeh, K Harbor UCLA Med Ctr, Div Nephrol & Hypertens, 1000 W Carson St,Harbor Mailbox 406, Torrance, CA 90509 USA Harbor UCLA Med Ctr 1000 W Carson St,Harbor Mailbox 406 Torrance CA USA 90509
Citazione:
K. Kalantar-Zadeh et al., "Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis", J AM S NEPH, 12(12), 2001, pp. 2797-2806

Abstract

Patients on maintenance hemodialysis (MHD) often show substantial reductions in quality of life (QoL). The SF36 (Short Form with 36 questions), a well-documented, self-administered QoL scoring system that includes eight independent scales and two main dimensions, has been widely used and validated. In 65 adult outpatients on MHD, the SF36 and its scales and dimensions, scored as a number between 0 and 100, and the nutritional and inflammatory state measured by subjective global assessment, near-infrared (NIR) body fat,body mass index (BMI), and pertinent laboratory values, including hemoglobin, albumin, and C-reactive protein were assessed. Twelve-month prospectivehospitalization rates and mortality were used as the clinical outcomes. Multivariate (case-mix) adjusted correlation coefficients were statistically significant between SF36 scores and serum albumin and hemoglobin concentrations. There were significant inverse correlations be-tween SF36 scores and the BMI and NIR body fat percentage. Hypoalbuminemic, anemic, and obese patients on MHD had a worse QoL. Prospective hospitalizations correlated significantly with the SF36 total score and its two main dimensions (r between -0.28 and -0.40). The Cox proportional regression relative risk of death foreach 10 unit decrease in SF36 was 2.07 (95% CI, 1.08 to 3.98; P = 0.02). Of the eight components and two dimensions of the SF36, the Mental Health dimension and the SF36 total score had the strongest predictive value for mortality. Thus, in patients on MHD the SF36 appears to have significant associations with measures of nutritional status, anemia, and clinical outcomes,including prospective hospitalization and mortality. Even though obesity, unlike undernutrition, is not generally an indicator of poor outcome in MHD, the SF36 may detect obese patients on MHD at higher risk for morbidity and mortality.

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Documento generato il 04/04/20 alle ore 15:15:44