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Titolo:
Simple and rapid determination of psoralens in topic solutions using liquid chromatography
Autore:
Cardoso, CAL; Honda, NK; Barison, A;
Indirizzi:
Univ Estadual Mato Grosso Sul, BR-79804970 Dourados, MS, Brazil Univ Estadual Mato Grosso Sul Dourados MS Brazil BR-79804970 BCMS, Brazil Univ Fed Mato Grosso Sul, Dept Quim, BR-79070900 Campo Grande, MS, Brazil Univ Fed Mato Grosso Sul Campo Grande MS Brazil BR-79070900 BC MS, Brazil
Titolo Testata:
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
fascicolo: 1-2, volume: 27, anno: 2002,
pagine: 217 - 224
SICI:
0731-7085(20020101)27:1-2<217:SARDOP>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
OXYGEN HETEROCYCLIC-COMPOUNDS; CITRUS ESSENTIAL OILS; QUANTITATIVE-DETERMINATION; IN-VITRO; FURANOCOUMARINS; FUROCOUMARINS; IDENTIFICATION; EXTRACTION; CELERY; HPLC;
Keywords:
liquid chromatography; psoralens; furanocoumarins; quantification;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Cardoso, CAL Univ Estadual Mato Grosso Sul, Caixa Postal 351, BR-79804970 Dourados, MS,Brazil Univ Estadual Mato Grosso Sul Caixa Postal 351 DouradosMS Brazil BR-79804970 BC
Citazione:
C.A.L. Cardoso et al., "Simple and rapid determination of psoralens in topic solutions using liquid chromatography", J PHARM B, 27(1-2), 2002, pp. 217-224

Abstract

A method for sample preparation and high-performance liquid chromatographydetection and quantification has been developed for the routine analysis of psoralen and bergapten, photosensitizing compounds, in topic solutions employed in Brazil for treatment of vitiligo and psoriasis. The linearity, accuracy, the inter- and intra-day precision of the procedure were evaluated. The calibration curve for psoralen and bergapten were linear in the range 1.0-20.0 mug ml(-1). The best recoveries of the psoralens in the topic solutions analysed were 96.3-98.2%. The percentage coefficient of variation of the quantitative analysis of the psoralens in the product analyses was within 5%. (C) 2002 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 11:43:38