Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Evaluation of Stratus (R) CS stat fluorimetric analyser for measurement ofcardiac markers troponin I (cTnl), creatine kinase MB (CK-MB), and myoglobin
Autore:
Beneteau-Burnat, B; Baudin, B; Vaubourdolle, M;
Indirizzi:
AP HP, Hop St Antoine, Serv Biochim A, F-75571 Paris 12, France AP HP Paris France 12 Antoine, Serv Biochim A, F-75571 Paris 12, France
Titolo Testata:
JOURNAL OF CLINICAL LABORATORY ANALYSIS
fascicolo: 6, volume: 15, anno: 2001,
pagine: 314 - 318
SICI:
0887-8013(2001)15:6<314:EOS(CS>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE CORONARY SYNDROMES; ACUTE CHEST PAIN; MYOCARDIAL-INFARCTION; TRIAGE;
Keywords:
Troponin I; CK-MB; myoglobin; immunoassay;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Beneteau-Burnat, B AP HP, Hop St Antoine, Serv Biochim A, 184 Rue Fbg St Antoine, F-75571 Paris 12, France AP HP 184 Rue Fbg St Antoine Paris France12 2, France
Citazione:
B. Beneteau-Burnat et al., "Evaluation of Stratus (R) CS stat fluorimetric analyser for measurement ofcardiac markers troponin I (cTnl), creatine kinase MB (CK-MB), and myoglobin", J CL LAB AN, 15(6), 2001, pp. 314-318

Abstract

Myoglobin, CK-MB, and Troponin I (cTnl) are cardiac muscle necrosis markers that are useful for detecting acute myocardial infarction (AMI). The Stratus (R) CS (Dade Behring, Inc.) is a discrete fluorimetric immunoassay analyser designed for the determination of the three cardiac markers from a single sample of whole blood or plasma. Overall analytical performances of theStratus (R) CS provided by Dade Behring were evaluated according to the French Society of Clinical Biology guidelines. Within-run imprecision (n = 20) for the three parameters at three levels gave values under 5%, whereas CVs for between-run imprecision (n = 20) were under 6%. The sensitivities were 0.03 mug/L for cTnl and 0.4 mug/L for CK-MB. Linearities extended from 0-50 mug/L for cTnl, 0-140 mug/L for CK-MB, and 1-900 mug/L for myoglobin. The results, particularly those obtained on whole-blood samples, correlated well with those obtained on Stratus (R) II. We did not find any interferencewith haemolysis, icterus, or lipemia. The system was very easy to use, andfulfills the requirements for the analysis of the three cardiac markers inpatients with acute chest pain in emergency situations. J. Clin. Lab. Anal. 15:314-318, 2001. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 10:32:44