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Titolo:
Effects of mobile phone type signals on calcium levels within human leukaemic T-cells (Jurkat cells)
Autore:
Cranfield, CG; Wood, AW; Anderson, V; Menezes, KG;
Indirizzi:
Swinburne Univ Technol, Sch Biophys Sci & Elect Engn, Melbourne, Vic, Australia Swinburne Univ Technol Melbourne Vic Australia Melbourne, Vic, Australia
Titolo Testata:
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
fascicolo: 12, volume: 77, anno: 2001,
pagine: 1207 - 1217
SICI:
0955-3002(200112)77:12<1207:EOMPTS>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYTOPLASMIC CA2+ OSCILLATIONS; INTRACELLULAR CALCIUM; MAGNETIC-FIELDS; ELECTROMAGNETIC-FIELDS; BRAIN-TISSUE; FREQUENCY; LINE; EXPOSURE; CA-2+; HZ;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Wood, AW Swinburne Univ Technol, Sch Biophys Sci & Elect Engn, Melbourne, Vic, Australia Swinburne Univ Technol Melbourne Vic Australia , Vic, Australia
Citazione:
C.G. Cranfield et al., "Effects of mobile phone type signals on calcium levels within human leukaemic T-cells (Jurkat cells)", INT J RAD B, 77(12), 2001, pp. 1207-1217

Abstract

Purpose: To test whether exposure to simulated GSM mobile phone signals (915 MHz, 2 W kg(-1)) influences the concentration of calcium or calcium signalling patterns in a human lymphocyte cell line. Materials and methods: The radiofrequency (RF) energy was delivered via a coaxial applicator to a perfused chamber where cells adherent to a thin glass coverslip were imaged by laser scanning confocal microscopy. Cell calcium concentration, estimated from Fluo-3 fluorescence, was monitored over two10-min periods; control followed by exposed/sham, with exposure status assigned in a blind and randomized fashion. Both continuous wave (CW) and pulsed wave (PW) RF (on both phytohaemagglutanin-activated and unactivated cells) were studied (with an equal number of sham exposures) on 100 cells per category (total 800 cells). Results: No significant changes were noted for the following: regression slope of calcium fluorescence; mean calcium concentration; number of calcium'spikes' in each 10 min; or mean height of these 'spikes'. The average frequency from Fourier spectra of these periods showed significant alteration in one category only: PW exposure of activated cells. Conclusions : There is no clear indication that RF emissions from mobile phones are associated with any changes in calcium levels or calcium signalling in lymphocytes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 19:30:04