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Titolo:
Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy
Autore:
Jenni, R; Oechslin, E; Schneider, J; Jost, CA; Kaufmann, PA;
Indirizzi:
Univ Zurich Hosp, Ctr Cardiovasc, Div Echocardiog, CH-8091 Zurich, Switzerland Univ Zurich Hosp Zurich Switzerland CH-8091 CH-8091 Zurich, Switzerland Univ Zurich Hosp, Dept Pathol, CH-8091 Zurich, Switzerland Univ Zurich Hosp Zurich Switzerland CH-8091 CH-8091 Zurich, Switzerland
Titolo Testata:
HEART
fascicolo: 6, volume: 86, anno: 2001,
pagine: 666 - 671
SICI:
1355-6037(200112)86:6<666:EAPCOI>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
TWO-DIMENSIONAL ECHOCARDIOGRAPHY; ISOLATED NONCOMPACTION; MYOCARDIAL SINUSOIDS; SPONGY MYOCARDIUM; PERSISTENCE; ADULTS;
Keywords:
isolated ventricular non-compaction; morphological criteria; cardiomyopathy; echocardiography; pathology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Jenni, R Univ Zurich Hosp, Ctr Cardiovasc, Div Echocardiog, Raemistr 100, CH-8091 Zurich, Switzerland Univ Zurich Hosp Raemistr 100 Zurich Switzerland CH-8091 zerland
Citazione:
R. Jenni et al., "Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy", HEART, 86(6), 2001, pp. 666-671

Abstract

Aim-To determine clear cut echo cardiographic criteria for isolated ventricular non-compaction (IVNC), a cardiomyopathy as yet "unclassified" by the World Health Organization. The disease is not widely known and its diagnosis mostly missed. Methods and results-In seven out of a series of 34 patients with IVNC the in vivo echocardiographic characteristics were validated against the anatomical examination of the heart removed after death in four and due to heart transplantation in three patients. Four morphological criteria diagnostic for IVNC were found. (1) Coexisting cardiac abnormalities were absent (by definition). (2) A two layer structure was seen, with a compacted thin epicardial band and a much thicker non-compacted endocardial layer of trabecular meshwork with deep endomyocardial spaces. A maximal end systolic ratio of non-compacted to compacted layers of > 2 is diagnostic. (3) The predominant localisation of the pathology was to mid-lateral (seven of seven patients),apical (six), and mid-inferior (seven) areas. The pathological preparations confirmed the echocardiographic findings. Concomitant regional hypokinesia was not confined to the non-compacted segments. (4) There was colour Doppler evidence of deep perfused intertrabecular recesses. Conclusions-Four clear cut echo cardiographic diagnostic criteria were established. It is suggested that the WHO classification of cardiomyopathies be reconsidered to include IVNC as a distinct cardiomyopathy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:28:36