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Titolo:
Hyperbaric oxygen modulates antioxidant enzyme activity in rat skeletal muscles
Autore:
Gregorevic, P; Lynch, GS; Williams, DA;
Indirizzi:
Univ Melbourne, Dept Physiol, Melbourne, Vic 3010, Australia Univ Melbourne Melbourne Vic Australia 3010 elbourne, Vic 3010, Australia
Titolo Testata:
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 1, volume: 86, anno: 2001,
pagine: 24 - 27
SICI:
1439-6319(200111)86:1<24:HOMAEA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENERATION; EXERCISE;
Keywords:
hyperbaric oxygen; superoxide dismutase; glutathione peroxidase; catalase; reactive oxygen species;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Williams, DA Univ Melbourne, Dept Physiol, Melbourne, Vic 3010, Australia Univ Melbourne Melbourne Vic Australia 3010 3010, Australia
Citazione:
P. Gregorevic et al., "Hyperbaric oxygen modulates antioxidant enzyme activity in rat skeletal muscles", EUR J A PHY, 86(1), 2001, pp. 24-27

Abstract

In skeletal muscle the activity of the enzymatic antioxidants superoxide dismutase ( OD), glutathione peroxidase (GPx) and catalase (CAT) is regulated in response to generation of reactive oxygen species (ROS). Increased activity of these enzymes is observed after repeated bouts of aerobic exercise. a potent stimulus for intracellular ROS production. Hyperbaric oxygen (HBO) inhalation also stimulates intracellular ROS production although the effects of HBO on skeletal muscle SOD. GPx and CAT activity have not been studied. We tested the hypothesis that SOD, GPx and CAT activity is modulated in skeletal muscles in response to acute and repeated HBO administration. Inadult male rats acute HBO inhalation (60 min at 3 atmospheres absolute) reduced catalase activity by approximately 51% in slow-twitch soleus muscles. Additionally, repeated HBO inhalation (twice daily for 28 days) increased Mn2+-superoxide dismutase activity by approximately 241% in fast-twitch extensor digitorum longus muscles. We conclude that both acute and repeated HBO inhalation can alter enzymatic antioxidant activity in skeletal muscles.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 19:29:58