Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Use of dobutamine stress echocardiography in detecting silent myocardial ischaemia in asymptomatic diabetic patients: a comparison with thallium scintigraphy and exercise testing
Autore:
Penfornis, A; Zimmermann, C; Boumal, D; Sabbaht, A; Meneveau, N; Gaultier-Bourgeois, S; Bassand, JP; Bernard, Y;
Indirizzi:
Univ Hosp, Dept Endocrinol, Besancon, France Univ Hosp Besancon FranceUniv Hosp, Dept Endocrinol, Besancon, France Univ Hosp, Dept Cardiol, Besancon, France Univ Hosp Besancon FranceUniv Hosp, Dept Cardiol, Besancon, France Univ Hosp, Dept Nucl Med, Besancon, France Univ Hosp Besancon FranceUniv Hosp, Dept Nucl Med, Besancon, France
Titolo Testata:
DIABETIC MEDICINE
fascicolo: 11, volume: 18, anno: 2001,
pagine: 900 - 905
SICI:
0742-3071(200111)18:11<900:UODSEI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; PROGNOSTIC VALUE; HEART-DISEASE; HIGH-RISK; MELLITUS; PREDICTION; ISCHEMIA;
Keywords:
dobutaimine-atropine stress echocardiography; thallium-201 single-photon emission computed tomography; coronary artery disease; diabetes;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Penfornis, A Hop Jean Minjoz, Serv Endocrinol, F-25030 Besancon, France Hop Jean Minjoz Besancon France F-25030 30 Besancon, France
Citazione:
A. Penfornis et al., "Use of dobutamine stress echocardiography in detecting silent myocardial ischaemia in asymptomatic diabetic patients: a comparison with thallium scintigraphy and exercise testing", DIABET MED, 18(11), 2001, pp. 900-905

Abstract

Aims Silent myocardial ischaemia is frequent in diabetic patients. The aimof this study, was to compare the efficacy of thallium-20 I single-photon emission Computed tomograph (Tl-201 SPECT) coupled with exercise stress testing (EST), and dobutamine stress echocardiography (DSE) in the detection of asymptomatic coronary artery disease. Methods Fifty-six asymptomatic diabetic patients, with a known duration ofdiabetes >15 years for Type 1 and >5 years for Type 2, having at least three added risk factors, but without rest ECG abnormalities, were enrolled inthis prospective study. All of them were submitted to DSE with a maximum infusion rate of 40 mug/kg per min dobutamine +/- i.v. atropine, and to Tl-201 SPECT coupled with EST. Coronary angiography was performed if at least one test was abnormal. Results Diabetic patients were 37 males and 19 females, aged mean (SD) 60 /- 10 years, 10 Type 1 and 46 Type 2, with a known duration of disease of mean (SID) 17 +/- 9 years. Feasibility of DSE was 91%. No serious complication occurred during the test. Coronary angiography was performed in 26 patients (47%), 17 were abnormal (30% of the whole group): six patients had a one-vessel, six a two-vessel and five a three-vessel disease. Predictive positive value was 69%. for DSE, 75% for Tl-201 SPECT and 60% for EST. DSE wasfalsely negative in four cases vs. eight for Tl-201 SPECT and nine for EST. Conclusions Asymptomatic coronary disease is common in diabetes associatedwith other risk factors. DSE appears useful in its detection and a good alternative to Tl-201 SPECT.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:29:09