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Titolo:
Morphogenetic domains in the yolk syncytial layer of axiating zebrafish embryos
Autore:
DAmico, LA; Cooper, MS;
Indirizzi:
Univ Washington, Dept Zool, Seattle, WA 98195 USA Univ Washington SeattleWA USA 98195 on, Dept Zool, Seattle, WA 98195 USA Univ Washington, Ctr Dev Biol, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Ctr Dev Biol, Seattle, WA 98195 USA
Titolo Testata:
DEVELOPMENTAL DYNAMICS
fascicolo: 4, volume: 222, anno: 2001,
pagine: 611 - 624
SICI:
1058-8388(200112)222:4<611:MDITYS>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
NODAL-RELATED SIGNALS; HOMEOBOX GENE; XENOPUS-LAEVIS; MESODERM INDUCTION; CELL LINEAGE; BETA-CATENIN; ANTERIOR NEUROECTODERM; HOMEODOMAIN PROTEIN; EARLY EMBRYOGENESIS; SPEMANNS ORGANIZER;
Keywords:
morphogenesis; yolk; yolk syncytial layer (YSL); convergence; extension; convergent-extension; nuclei; cell; movements; gastrulation; zebrafish-; teleost; epiboly; vital-staining; endoderm; extraembryonic; syncytial; involution; mesoderm; epiblast; hypoblast; germ layers; dorsal; organizer; time-lapse;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
81
Recensione:
Indirizzi per estratti:
Indirizzo: D'Amico, LA Univ Calif San Francisco, Dept Biochem & Biophys, Box 0448,513Parnassus Ave, San Francisco, CA 94143 USA Univ Calif San Francisco Box 0448,513 Parnassus Ave San Francisco CA USA 94143
Citazione:
L.A. D'Amico e M.S. Cooper, "Morphogenetic domains in the yolk syncytial layer of axiating zebrafish embryos", DEV DYNAM, 222(4), 2001, pp. 611-624

Abstract

The yolk syncytial layer (YSL) of the teleostean yolk cell is known to play important roles in the induction of cellular mesendoderm, as well as the patterning of dorsal tissues. To determine how this extraembryonic endodermal compartment is subdivided and morphologically transformed during early development, we have examined collective movements of vitally stained YSL nuclei in axiating zebrafish embryos by using four-dimensional confocal microscopy. During blastulation, gastrulation, and early segmentation, zebrafishYSL nuclei display several highly patterned movements, which are organizedinto spatially distinct morphogenetic domains along the anterior-posteriorand dorsal-ventral axes. During the late blastula period, with the onset of epiboly, nuclei throughout the YSL initiate longitudinal movements that are directed along the animal-vegetal axis. As epiboly progresses, nuclei progressively recede from the advancing margin of the epibolic YSL. However, a small group of nuclei is retained at the YSL margin to form a constricting blastoporal ring. During mid-gastrulation, YSL nuclei undergo convergent-extension behavior toward the dorsal midline, with a subset of nuclei forming an axial domain that underlies the notochord. These highly patterned movements of YSL nuclei share remarkable similarities to the morphogenetic movements of deep cells in the overlying zebrafish blastoderm. The macroscopicshape changes of the zebrafish yolk cell, as well as the morphogenetic movements of its YSL nuclei, are homologous to several morphogenetic behaviorsthat are regionally expressed within the vegetal endodermal cell mass of gastrulating Xenopus embryos. In contrast to the cellular endoderm. of Xenopus, the dynamics of zebrafish YSL show that a syncytial endodermal germ layer can express a temporal sequence of morphogenetic domains without undergoing progressive steps of cell fate restriction. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/05/20 alle ore 04:08:07