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Titolo:
Coronary artery calcification in older adults to age 99 - Prevalence and risk factors
Autore:
Newman, AB; Naydeck, BL; Sutton-Tyrrell, K; Feldman, A; Edmundowicz, D; Kuller, LH;
Indirizzi:
Univ Pittsburgh, Sch Med, Div Geriatr Med, Pittsburgh, PA 15213 USA Univ Pittsburgh Pittsburgh PA USA 15213 atr Med, Pittsburgh, PA 15213 USA Univ Pittsburgh, Sch Med, Dept Epidemiol, Pittsburgh, PA 15213 USA Univ Pittsburgh Pittsburgh PA USA 15213 idemiol, Pittsburgh, PA 15213 USA
Titolo Testata:
CIRCULATION
fascicolo: 22, volume: 104, anno: 2001,
pagine: 2679 - 2684
SICI:
0009-7322(20011127)104:22<2679:CACIOA>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
BEAM COMPUTED-TOMOGRAPHY; CARDIOVASCULAR HEALTH; HEART-DISEASE; CHOLESTEROL; CALCIUM; EXTENT; MEN; ATHEROSCLEROSIS; ASSOCIATION; PREDICTION;
Keywords:
calcium; coronary diseases; aging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Newman, AB Univ Pittsburgh, Sch Med, Div Geriatr Med, 3520 5th Ave,Suite 300, Pittsburgh, PA 15213 USA Univ Pittsburgh 3520 5th Ave,Suite 300 Pittsburgh PA USA 15213
Citazione:
A.B. Newman et al., "Coronary artery calcification in older adults to age 99 - Prevalence and risk factors", CIRCULATION, 104(22), 2001, pp. 2679-2684

Abstract

Background-Coronary artery calcification has been proposed as a noninvasive method to assess cardiovascular disease (CVD) risk. However, the prevalence and risk factors for coronary artery calcification in populations > 65 years have not been well studied. Methods and Results-Electron beam tomography was performed to assess coronary artery calcium (CAC) in 614 older adults aged, on average, 80 years (range, 67 to 99 years); 367 (60%) were women, and 143 (23%) were black. Calcium scores ranged from 0 to 5459. Median scores were 622 for men and 205 forwomen. Scores increased by age and were lower in blacks than in whites. Nine percent of subjects (n=57) had no CAC, and 31% (n=190) had a score lowerthan 100. A history of CVD was associated with calcium score. Age, male sex, white race, CVD, triglyceride level, pack-years of smoking, and asthma, emphysema, or bronchitis (chronic obstructive pulmonary disease) were independently associated with CAC score in the fourth quartile. Conclusions-A wide range of CAC scores was observed, suggesting, adaptation with aging. CAC may have potential to predict CVD in older adults, but this remains to be determined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 21:46:29