Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
3-benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents
Autore:
Chaouni-Benabdallah, A; Galtier, C; Allouchi, H; Kherbeche, A; Chavignon, O; Teulade, JC; Witvrouw, M; Pannecouque, C; Snoeck, R; Andrei, G; Balzarini, J; De Clercq, E; Fauvelle, F; Enguehard, C; Gueiffier, A;
Indirizzi:
Fac Pharm Tours, EA Grp Rech Chim Heterocycl & Therapeut, Chim Therapeut Lab, F-37200 Tours, France Fac Pharm Tours Tours France F-37200 herapeut Lab, F-37200 Tours, France Univ Sidi Mohamed Ben Abdellah, Ecole Super Technol Fes, Lab Catalyse & Environm, Fes, Morocco Univ Sidi Mohamed Ben Abdellah Fes Morocco yse & Environm, Fes, Morocco Fac Pharm Tours, Chim Phys Lab, F-37200 Tours, France Fac Pharm Tours Tours France F-37200 him Phys Lab, F-37200 Tours, France Fac Pharm Clermont Ferrand, Chim Organ Lab, F-63001 Clermont Ferrand, France Fac Pharm Clermont Ferrand Clermont Ferrand France F-63001 rrand, France Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium Katholieke Univ Leuven Louvain Belgium B-3000 s, B-3000 Louvain, Belgium BCM, Ctr Rech Serv Sante Armees, F-38702 La Tronche, France BCM La Tronche France F-38702 v Sante Armees, F-38702 La Tronche, France
Titolo Testata:
CHEMICAL & PHARMACEUTICAL BULLETIN
fascicolo: 12, volume: 49, anno: 2001,
pagine: 1631 - 1635
SICI:
0009-2363(200112)49:12<1631:3UATDA>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
REVERSE-TRANSCRIPTASE INHIBITORS; TYPE-1 HIV-1 INFECTIONS; VIRUS; NNRTIS; IMIDAZO<1,2-A>PYRIDINES; SERIES;
Keywords:
imidazo[1,2-a]pyridine; cytomegalovirus; phenylthioureido; crystallographic data;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Gueiffier, A Fac Pharm Tours, EA Grp Rech Chim Heterocycl & Therapeut, Chim Therapeut Lab, 31 Ave Monge, F-37200 Tours, France Fac Pharm Tours 31 AveMonge Tours France F-37200 rs, France
Citazione:
A. Chaouni-Benabdallah et al., "3-benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents", CHEM PHARM, 49(12), 2001, pp. 1631-1635

Abstract

This work reports the synthesis and the antiviral activities of 3-benzamido, 3-phenylureido and 3-phenyl-thioureido derivatives in the imidazo[1,2-a]pyridine series. The structure was proven by NMR spectroscopy. The synthesized compounds were evaluated against a large number of viruses. The 3-phenylthioureido derivative 7 showed moderate activity against human cytomegalovirus (HCMV) in vitro. The crystallographic data for 8 are also reported andexplain the absence of activity against human immunodeficiency virus (HIV).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 14:39:56