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Titolo:
Neural circuitry of the kidney: NO-containing neurons
Autore:
Weiss, ML; Chowdhury, SI; Patel, KP; Kenney, MJ; Huang, J;
Indirizzi:
Kansas State Univ, Coll Vet Med, Dept Anat, Manhattan, KS 66506 USA KansasState Univ Manhattan KS USA 66506 pt Anat, Manhattan, KS 66506 USA Kansas State Univ, Coll Vet Med, Dept Physiol, Manhattan, KS 66506 USA Kansas State Univ Manhattan KS USA 66506 Physiol, Manhattan, KS 66506 USA Kansas State Univ, Coll Vet Med, Dept Diagnost Med Pathobiol, Manhattan, KS 66506 USA Kansas State Univ Manhattan KS USA 66506 thobiol, Manhattan, KS 66506 USA Kansas State Univ, Coll Med, Dept Physiol, Manhattan, KS 66506 USA Kansas State Univ Manhattan KS USA 66506 Physiol, Manhattan, KS 66506 USA
Titolo Testata:
BRAIN RESEARCH
fascicolo: 2, volume: 919, anno: 2001,
pagine: 269 - 282
SICI:
0006-8993(20011123)919:2<269:NCOTKN>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
NITRIC-OXIDE SYNTHASE; SYMPATHETIC PREGANGLIONIC NEURONS; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; ROSTRAL VENTROLATERAL MEDULLA; RENAL AFFERENT PATHWAYS; RAT SPINAL-CORD; NADPH-DIAPHORASE; PSEUDORABIES VIRUS; GENE-EXPRESSION; BRAIN-STEM;
Keywords:
transneuronal transport; herpesvirus; Sprague-Dawley rat; immunocytochemistry; neuronal isoform of nitric oxide synthase; sympathetic motor pathway;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
60
Recensione:
Indirizzi per estratti:
Indirizzo: Weiss, ML Kansas State Univ, Coll Vet Med, Dept Anat, Manhattan, KS 66506 USA Kansas State Univ Manhattan KS USA 66506 anhattan, KS 66506 USA
Citazione:
M.L. Weiss et al., "Neural circuitry of the kidney: NO-containing neurons", BRAIN RES, 919(2), 2001, pp. 269-282

Abstract

The neurons synthesizing nitric oxide (NO) that are part of the renal sympathetic pathways were located by double-staining for the neuronal isoform of nitric oxide synthase (nNOS) using immunocytochemistry to identify NO-synthesizing neurons and transneuronal tracing following infection of the leftkidney with pseudorabies virus (PRV). Following kidney injection with PRV,the animals survived 4-day post-inoculation prior to sacrifice and tissue processing. PRV-infected neurons that double-stained for nNOS were found inthe paraventricular hypothalamic nucleus (PVN), the raphe obscurus nucleus(ROb), the ventromedial medulla (VMM), the rostral ventrolateral medulla (rVLM) and the A5 cell group. In the thoracolumbar spinal cord, nNOS neuronsco-localized with PRV-infected cells in the dorsal horn in laminae I, III-V ipsilateral to the injected kidney and in lamina X, the intermediolateralcell column, the lateral funiculus, the intercalated nucleus and the central autonomic area. We conclude that NO synthesizing cells may significantlyaffect renal autonomic pathways in the rat by interacting with the renal sensory and sympathomotor circuitry at multiple sites. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 01:36:21