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Titolo:
RNP localization and transport in yeast
Autore:
Chartrand, P; Singer, RH; Long, RM;
Indirizzi:
Albert Einstein Coll Med, Dept Anat & Struct Biol, Bronx, NY 10461 USA Albert Einstein Coll Med Bronx NY USA 10461 uct Biol, Bronx, NY 10461 USA Albert Einstein Coll Med, Dept Cell Biol, Bronx, NY 10461 USA Albert Einstein Coll Med Bronx NY USA 10461 ell Biol, Bronx, NY 10461 USA Med Coll Wisconsin, Dept Microbiol & Mol Genet, Milwaukee, WI 53226 USA Med Coll Wisconsin Milwaukee WI USA 53226 Genet, Milwaukee, WI 53226 USA
Titolo Testata:
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
, volume: 17, anno: 2001,
pagine: 297 - 310
SICI:
1081-0706(2001)17:<297:RLATIY>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
ASH1 MESSENGER-RNA; GREEN FLUORESCENT PROTEIN; SACCHAROMYCES-CEREVISIAE; ACTIN CYTOSKELETON; BUDDING YEAST; STRUCTURAL ELEMENTS; BINDING PROTEIN; MYOSIN MOTOR; MORPHOGENESIS; MYO4P;
Keywords:
ASH1 mRNA; RNA localization; She proteins; locasome; myosin;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Chartrand, P Albert Einstein Coll Med, Dept Anat & Struct Biol, Bronx, NY 10461 USA Albert Einstein Coll Med Bronx NY USA 10461 nx, NY 10461 USA
Citazione:
P. Chartrand et al., "RNP localization and transport in yeast", ANN R C DEV, 17, 2001, pp. 297-310

Abstract

The localization of mRNAs is used by various types of polarized cells to locally translate specific proteins, which restricts their distribution to aparticular sub-region of the cytoplasm. This mechanism of protein sorting is involved in major biological processes such as asymmetric cell division,oogenesis, cellular motility, and synapse formation. With the finding of localized mRNAs in the yeast Saccharomyces cerevisiae, it is now possible tobenefit from the powerful yeast laboratory tools to explore the molecular basis of RNA localization. Because mRNA transport and localization in yeastshare many features with RNA localization in higher eukaryotes, including the formation of a large ribonucleoprotein (RNP) localization complex, the requirement of a polarized cytoskeleton and molecular motors, and the role of nuclear RNA-binding proteins in cytoplasmic localization, the yeast can be used as a paradigm for unraveling the molecular aspects of this process. This review summarizes the current knowledge on RNP transport and localization in yeast.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 23:56:06