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Titolo:
The effect of low doses of naloxone on the preovulatory surge of LH and onthe onset and duration of oestrus in the ewe with induced oestrus during the non-breeding season
Autore:
Fuentes, VO; Sanchez, V; Rosiles, R; Fuentes, PI;
Indirizzi:
Natl Autonomous Univ Mexico, Fac Med Vet, Dept Physiol, Copilco 04510, DF,Mexico Natl Autonomous Univ Mexico Copilco DF Mexico 04510 ilco 04510, DF,Mexico
Titolo Testata:
ANIMAL REPRODUCTION SCIENCE
fascicolo: 3-4, volume: 65, anno: 2001,
pagine: 225 - 230
SICI:
0378-4320(20010330)65:3-4<225:TEOLDO>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENDOGENOUS OPIOID MODULATION; LUTEINIZING-HORMONE RELEASE; ANESTROUS EWES; MATURE EWES; SECRETION; INVOLVEMENT; MORPHINE;
Keywords:
ewe; oestrus; naloxone; LH surge;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Fuentes, VO Natl Autonomous Univ Mexico, Fac Med Vet, Dept Physiol, Copilco 04510, DF,Mexico Natl Autonomous Univ Mexico Copilco DF Mexico 04510 DF,Mexico
Citazione:
V.O. Fuentes et al., "The effect of low doses of naloxone on the preovulatory surge of LH and onthe onset and duration of oestrus in the ewe with induced oestrus during the non-breeding season", ANIM REPROD, 65(3-4), 2001, pp. 225-230

Abstract

The objective of this work was to study the effect of the endogenous opiate peptide (EOP) antagonist, naloxone, on the preovulatory LH surge and on the time of onset and duration of oestrus in the ewe with induced oestrus during the non-breeding season. Forty Suffolk X Hampshire ewes 2-3-years-old and 50 +/-4 kg were studied, ewes were divided at random in two groups of 20, housed in open paddocks under natural photoperiod (19 degrees latitude N); were fed with hay and commercial pellets, and provided water ad libitum. Group one received an intravaginal sponge with 45 mg of medroxiprogesterone acetate for 14 days, and upon sponge withdrawal 250 IU of eCG was administered i.m. Group two received the same treatment as group I but in additionthey received two i.m. injections of 0.5 mg of naloxone, one given on sponge withdrawal and the second 24 h later (total dose 1.0 mg). Oestrus in naloxone-treated ewes was present 32 +/- 2 h and in control ewes in 35 +/- 3 hafter sponge withdrawal. Duration of oestrus in control ewes was shorter (27 +/- 2.5 h), than naloxone-treated ewes (39 +/- 6h); (P < 0.0001). The LHsurge in naloxone-treated ewes was initiated 5 h after onset of oestrus, and 8 h after onset of oestrus in control ewes, and the difference was significative (P < 0.0006). It was concluded that EOP are important modulators of reproductive function in the ewe. (C) 2001 Published by Elsevier Science B.V.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 22:32:19