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Titolo:
Expression of bone morphogenetic protein-5 gene during chick heart development: Possible roles in valvuloseptal endocardial cushion formation
Autore:
Yamagishi, T; Nakajima, Y; Nishimatsu, SI; Nohno, T; Ando, K; Nakamura, H;
Indirizzi:
Saitama Med Sch, Dept Anat, Moroyama, Saitama 3500495, Japan Saitama Med Sch Moroyama Saitama Japan 3500495 ma, Saitama 3500495, Japan Kawasaki Med Univ, Dept Mol Biol, Okayama, Japan Kawasaki Med Univ Okayama Japan Med Univ, Dept Mol Biol, Okayama, Japan
Titolo Testata:
ANATOMICAL RECORD
fascicolo: 4, volume: 264, anno: 2001,
pagine: 313 - 316
SICI:
0003-276X(200112)264:4<313:EOBMPG>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
INDUCTION; EMBRYOS; SYSTEM;
Keywords:
BMP5; heart development; myocardial differentiation; cushion tissue formation; chick embryo;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Yamagishi, T Saitama Med Sch, Dept Anat, 38 Morohongo, Moroyama, Saitama 3500495, Japan Saitama Med Sch 38 Morohongo Moroyama Saitama Japan 3500495 n
Citazione:
T. Yamagishi et al., "Expression of bone morphogenetic protein-5 gene during chick heart development: Possible roles in valvuloseptal endocardial cushion formation", ANAT REC, 264(4), 2001, pp. 313-316

Abstract

The bone morphogenetic protein (BMP) family, comprising multifunctional peptide growth factors, regulates many developmental processes in a variety of tissues. We examined the spatiotemporal expression of BMP5 by in situ hybridization in chick embryonic hearts from stages 5 to 33. The BMP5 gene wasfirst expressed in the endoderm underlying the precardiac mesoderm at stages 5 to 8. Thereafter, BMP5 expression was restricted to the myocardium. ofthe atrioventricular (AV) canal and outflow tract (OT) regions, where the valvuloseptal endocardial cushion tissue is induced. These results suggest that BMP5 may play important roles not only in myocardial differentiation, but also in the formation and maintenance of endocardial cushion tissue. Anat Rec 264:313-316, 2001. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 04:01:24