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Titolo:
Comparative efficacy and tolerability of two direct-to-consumer tooth whitening systems
Autore:
Gerlach, RW; Barker, ML; Sagel, PA;
Indirizzi:
Procter & Gamble Co, Mason, OH 45040 USA Procter & Gamble Co Mason OH USA45040 r & Gamble Co, Mason, OH 45040 USA
Titolo Testata:
AMERICAN JOURNAL OF DENTISTRY
fascicolo: 5, volume: 14, anno: 2001,
pagine: 267 - 272
SICI:
0894-8275(200110)14:5<267:CEATOT>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARBAMIDE PEROXIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Gerlach, RW Procter & Gamble Co, 8700 Mason Montgomery Rd, Mason, OH 45040USA Procter & Gamble Co 8700 Mason Montgomery Rd Mason OH USA 45040
Citazione:
R.W. Gerlach et al., "Comparative efficacy and tolerability of two direct-to-consumer tooth whitening systems", AM J DENT, 14(5), 2001, pp. 267-272

Abstract

Purpose: To compare the clinical response of two self-directed vital bleaching systems under market use conditions. Materials and Methods: A randomized, parallel-group clinical trial was conducted. A total of 20 healthy adults were randomized to either a 6.0% hydrogen peroxide strip-based bleachingsystem or a combination system involving a 10% carbamide peroxide gel in astock tray along with an anticavity whitening dentifrice and after-bleaching whitening mouthrinse. Only the maxillary arch was bleached over a 14-dayperiod. Subjects were evaluated at 3, 8 and 15 days. Efficacy was measuredobjectively using digital image analysis to derive individual color parameters (L*a*b*) and overall color change (DeltaE*). Results: After 14 days, the adjusted mean reduction in yellow (Deltab*) was -2.23 +/- 0.157 for the whitening strips compared to -0.97 +/- 0.188 for the combination system. This represented a highly statistically significant (P < 0.0001), two-fold superior reduction in yellowness for the whitening strip group compared to the marketed control. Similar results were seen for other color parameters, with the whitening strip group exhibiting twofold color improvement relativeto the tray/dentifrice/rinse combination. With respect to tolerability, tooth sensitivity and oral irritation were the most common findings. Considering event duration and severity, median bleaching tolerability severity-days scores were 0.07 and 0.58 for the strip and combination systems respectively, with these treatments differing statistically (P= 0.041) favoring the whitening strips.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/18 alle ore 08:06:23