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Titolo:
Production of tissue factor pathway inhibitor in cardiomyocytes and its upregulation by interleukin-1
Autore:
Kereveur, A; Enjyoji, K; Masuda, K; Yutani, C; Kato, H;
Indirizzi:
Natl Cardiovasc Ctr, Dept Etiol & Pathogenesis, Res Inst, Suita, Osaka 5658565, Japan Natl Cardiovasc Ctr Suita Osaka Japan 5658565 Suita, Osaka 5658565, Japan Natl Cardiovasc Ctr, Dept Pathol, Suita, Osaka 5658565, Japan Natl Cardiovasc Ctr Suita Osaka Japan 5658565 Suita, Osaka 5658565, Japan
Titolo Testata:
THROMBOSIS AND HAEMOSTASIS
fascicolo: 5, volume: 86, anno: 2001,
pagine: 1314 - 1319
SICI:
0340-6245(200111)86:5<1314:POTFPI>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
SMOOTH-MUSCLE CELLS; CORONARY-ARTERY DISEASE; HUMAN ENDOTHELIAL-CELLS; COAGULATION INHIBITOR; MYOCARDIAL-INFARCTION; MESSENGER-RNA; FACTOR EXPRESSION; IN-VIVO; TFPI; INJURY;
Keywords:
tissue factor pathway inhibitor; tissue factor; cardiomyocyte; interleukin-1;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Kato, H Natl Cardiovasc Ctr, Dept Etiol & Pathogenesis, Res Inst, 5-7-1 Fujihsirodai, Suita, Osaka 5658565, Japan Natl Cardiovasc Ctr 5-7-1 Fujihsirodai Suita Osaka Japan 5658565 n
Citazione:
A. Kereveur et al., "Production of tissue factor pathway inhibitor in cardiomyocytes and its upregulation by interleukin-1", THROMB HAEM, 86(5), 2001, pp. 1314-1319

Abstract

Tissue factor pathway inhibitor (TFPI) is a protease inhibitor that regulates tissue factor (TF) - initiated coagulation. We report here that cardiomyocytes express TFPI and the expression could be increased by lnterleukin-1(IL-1 beta). The TFPI expression in cardiomyocytes was confirmed by Northern blotting with rat cardiomyocytes and also by immunostaining with anti-TFPI antibody on human heart specimens from patients either with sarcoidosis, myocarditis or myocardial infarction. The regulation of TFPI expression in cardiomyocytes differs from that in endothelial cells because TFPI expression is not induced in human endothelial cells by IL-1 beta.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:39:02