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Titolo:
Changes of biophysical properties of the skin measured by non-invasive techniques after Q-switched Nd-YAG laser therapy in patients with nevus of Ota
Autore:
Kim, SD; Kim, SW; Huh, CH; Suh, DH; Eun, HC;
Indirizzi:
Seoul Natl Univ, Coll Med, Dept Dermatol, Seoul, South Korea Seoul Natl Univ Seoul South Korea ed, Dept Dermatol, Seoul, South Korea
Titolo Testata:
SKIN RESEARCH AND TECHNOLOGY
fascicolo: 4, volume: 7, anno: 2001,
pagine: 262 - 271
SICI:
0909-752X(200111)7:4<262:COBPOT>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSEPIDERMAL WATER-LOSS; PULSED-DYE-LASER; SELECTIVE PHOTOTHERMOLYSIS; STRATUM-CORNEUM; PIGMENTATION; ABSORPTION; HEMOGLOBIN; HYDRATION; ARGON;
Keywords:
non-invasive bioengineering; Q-switched Nd-YAG laser; nevus of Ota;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Eun, HC Seoul Natl Univ, Coll Med, Dept Dermatol, Seoul, South Korea SeoulNatl Univ Seoul South Korea Dermatol, Seoul, South Korea
Citazione:
S.D. Kim et al., "Changes of biophysical properties of the skin measured by non-invasive techniques after Q-switched Nd-YAG laser therapy in patients with nevus of Ota", SKIN RES TE, 7(4), 2001, pp. 262-271

Abstract

Background/aims: The aim of the study was to objectify the effect of a Q-switched Nd-YAG laser on Ota's nevus in view of barrier function, surface contour changes, dermal blood flow, surface color changes and sebum production rate. Methods: Fifteen Korean patients with nevus of Ota (between 14 and 54 years of age) were enrolled. All the patients were treated by Q-switched Nd-YAGlaser and followed up for 12 weeks. A reflectance spectrophotometer, a colorimeter, laser Doppler flowmetry, a Tewameter, a Corneometer and a Sebumeter were used to make measurements. Results: P values of less than 0.05 were regarded as statistically significant. In skin reflectance measurements, L* values declined for 4 weeks and increased at 12 weeks, indicating that the brightness of the lesions improved. a* values showed a significant increase at 2 and 4 weeks. On the contrary, b* values decreased at 2 weeks. Transepidermal water loss and dermal blood flux showed identical patterns, showing increases at 2 weeks. The waterholding capacity decreased at 2 and 4 weeks, and thereafter showed a delayed recovery. Casual sebum production increased at 4, 8 and 12 weeks. The loss of skin roughness was observed at 4 weeks, recovering at 12 weeks, although statistically insignificant. Reflex spectrophotometry did not reflect the changing properties of the skin. Conclusions: Our data suggest a useful model for evaluating physiologic skin changes after laser surgery in patients with nevus of Ota.

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Documento generato il 20/09/20 alle ore 07:14:34