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Titolo:
CT-guided percutaneous core biopsy. Effective accuracy, diagnostic utilityand effective costs.
Autore:
Wutke, R; Schmid, A; Fellner, F; Horbach, T; Kastl, S; Papadopoulos, T; Hohenberger, W; Bautz, W;
Indirizzi:
Univ Erlangen Nurnberg, Inst Diagnost Radiol, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-91054 -91054 Erlangen, Germany Univ Erlangen Nurnberg, Chirurg Klin Poliklin, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-91054 -91054 Erlangen, Germany Univ Erlangen Nurnberg, Inst Pathol, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-91054 -91054 Erlangen, Germany
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 11, volume: 173, anno: 2001,
pagine: 1025 - 1033
SICI:
1438-9029(200111)173:11<1025:CPCBEA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
GER
Soggetto:
AUTOMATED NEEDLE-BIOPSY; MUSCULOSKELETAL LESIONS; GUIDANCE; FLUOROSCOPY; PUNCTURE; TERM;
Keywords:
biopsy; CT; diagnostic utility; effective accuracy; effective costs;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Wutke, R Univ Erlangen Nurnberg, Inst Diagnost Radiol, Maximilianspl 1, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Maximilianspl 1 Erlangen Germany D-91054
Citazione:
R. Wutke et al., "CT-guided percutaneous core biopsy. Effective accuracy, diagnostic utilityand effective costs.", ROFO-F RONT, 173(11), 2001, pp. 1025-1033

Abstract

Purpose: The value of a diagnostic technique does not only depend on its sensitivity, specificity and accuracy, but also on how its results affect clinical management. This effect is represented by the values effective accuracy and the diagnostic utility which were determined for Cr-guided coaxial core biopsies in this study. Materials and methods: 180 consecutive biopsies were analyzed. The results were analyzed with the help of a logistic regression analysis with regard to the organ regions biopsied, the size of the needle used, and the number of tissue cores taken. Correct results that were not accepted as diagnostic clinically and resulted in additional biopsieswere scored together with the false results under negative utility coefficients. Results: The sensitivity, specificity and accuracy of all the tests amounted to 91.1%, 100%, and 93.3%, respectively. The diagnostic utility ofthe biopsies varied between 66% for the liver and pancreatic lesions, and 88% for the non-organ related retroperitoneum. In those cases where more than three tissue cores were taken the results were statistically significantly better in terms of effective accuracy and diagnostic utility. No significant differences were found with regard to different needle sizes in the biopsied organ regions. The lowest clinical acceptance was observed for the histological findings "scar tissue" and "inflammation". Conclusion: CT-guided coaxial biopsies offer a high degree of sensitivity, specificity and accuracy, as well as a low rate of therapeutically relevant complications. Withincreasing use of differentiated strategies in therapy for malignomas percutaneous biopsies play a very important role in the management of these diseases. Prospective studies should further evaluate the effective accuracy and diagnostic utility of core biopsies also in comparison to fine needle aspiration biopsies (FNAP).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 15:13:25