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Titolo:
Focal nodular hyperplasia: Morphologic and functional information from MR imaging with gadobenate dimeglumine
Autore:
Grazioli, L; Morana, G; Federle, MP; Brancatelli, G; Testoni, M; Kirchin, MA; Menni, K; Olivetti, L; Nicoli, N; Procacci, C;
Indirizzi:
Univ Brescia, Dept Radiol, I-25023 Brescia, Italy Univ Brescia Brescia Italy I-25023 , Dept Radiol, I-25023 Brescia, Italy Univ Pittsburgh, Med Ctr, Dept Radiol, Pittsburgh, PA 15260 USA Univ Pittsburgh Pittsburgh PA USA 15260 Radiol, Pittsburgh, PA 15260 USA Univ Verona, Dept Radiol, I-37100 Verona, Italy Univ Verona Verona ItalyI-37100 ona, Dept Radiol, I-37100 Verona, Italy Univ Verona, Dept Surg, I-37100 Verona, Italy Univ Verona Verona Italy I-37100 erona, Dept Surg, I-37100 Verona, Italy
Titolo Testata:
RADIOLOGY
fascicolo: 3, volume: 221, anno: 2001,
pagine: 731 - 739
SICI:
0033-8419(200112)221:3<731:FNHMAF>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATOCELLULAR-CARCINOMA; HEPATIC-LESIONS; CONTRAST AGENTS; LIVER-LESIONS; MN-DPDP; TUMORS; CT; MANGAFODIPIR; ENHANCEMENT; METASTASES;
Keywords:
gadobenate dimeglumine; iron; liver, focal nodular hyperplasia; liver neoplasm, diagnosis; liver neoplasm, MR; Magnetic resonance (MR), contrast; media; manganese;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Grazioli, L Univ Brescia, Dept Radiol, Piazzale Spedali Civili 1, I-25023 Brescia, Italy Univ Brescia Piazzale Spedali Civili 1 Brescia Italy I-25023
Citazione:
L. Grazioli et al., "Focal nodular hyperplasia: Morphologic and functional information from MR imaging with gadobenate dimeglumine", RADIOLOGY, 221(3), 2001, pp. 731-739

Abstract

PURPOSE: To determine whether gadobenate dimeglumine (Gd-BOPTA) is able toprovide morphologic and functional information for characterization of focal nodular hyperplasia (FNH). MATERIALS AND METHODS: Sixty-three consecutive patients with proved FNH were retrospectively examined. Magnetic resonance (MR) imaging with T2-weighted turbo spin-echo and T1-weighted gradient-echo sequences was performed. Images were acquired prior to and during the dynamic phase of contrast-material enhancement and 1-3 hours after administration of 0.1 mmol/kg Gd-BOPTA. Qualitative analysis of signal intensity and homogeneity on images in the various phases of the MR study and examination for the presence of central scar or atypical features were performed. On the basis of features observedin the precontrast and dynamic phases, lesions were defined as typical or atypical. Intensity and enhancement patterns of the lesions and scars were also evaluated in the delayed phase. RESULTS: One hundred FNHs were depicted on MR images. Seventy-nine of 100 lesions demonstrated typical morphologic and enhancement characteristics. On delayed phase images, 72% of 100 FNHs appeared hyperintense; 21%, isointense; and 7%, slightly hypointense. The delayed pattern of enhancement was homogeneous, heterogeneous, and peripheral in 58%, 22%, and 20% of 100 FNHs,respectively. Atypical morphologic features and lesion and/or scar enhancement were observed in 21 of 100 FNHs. On delayed phase images, 76% of 100 atypical FNHs appeared hyperintense, 14% isointense, and 10% slightly hypointense. Hyperintensity and isointensity allowed the correct characterizationin 90% of atypical FNHs. CONCLUSION: Gd-BOPTA during both dynamic and delayed phases provides morphologic and functional information for the characterization of FNH.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 06:04:32