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Titolo:
Vestibular schwannomas in children
Autore:
Pothula, VB; Lesser, T; Mallucci, C; May, P; Foy, P;
Indirizzi:
Univ Hosp Aintree, Dept Otolaryngol, Liverpool, Merseyside, England Univ Hosp Aintree Liverpool Merseyside England pool, Merseyside, England Univ Hosp Aintree, Dept Neurosurg, Liverpool, Merseyside, England Univ Hosp Aintree Liverpool Merseyside England pool, Merseyside, England
Titolo Testata:
OTOLOGY & NEUROTOLOGY
fascicolo: 6, volume: 22, anno: 2001,
pagine: 903 - 907
SICI:
1531-7129(200111)22:6<903:VSIC>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACOUSTIC NEUROMA; NEUROFIBROMATOSIS; CHILDHOOD;
Keywords:
sporadic; vestibular schwannoma; children;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Pothula, VB Royal Albert Edward Infirm, Wigan Lane, Wigan WB1 2NN, EnglandRoyal Albert Edward Infirm Wigan Lane Wigan England WB1 2NN d
Citazione:
V.B. Pothula et al., "Vestibular schwannomas in children", OTOL NEURO, 22(6), 2001, pp. 903-907

Abstract

Objective: This article highlights the clinical presentation and management issues of unilateral vestibular schwannomas in children. We demonstrate how the presentation differs from neurofibromatosis type 2 (NF2) and from adult unilateral vestibular schwannomas. Study Design: This article is composed of a series of three cases and a literature review. Setting: The study was performed at a university hospital (tertiary referral center). Patients: Three children, aged 9, 11, and 13 years, with histologically confirmed vestibular schwannomas were studied. All children under 16 years ofage in the world literature with unilateral vestibular schwannomas were reviewed. Intervention: Analysis of presentation and surgical management of these three children and those children reported in the literature. Main Outcome Measure: Pattern of presentation relative to children with NF2 and people with adult unilateral vestibular schwannomas. Results: Two patients had multiple cranial nerve weakness and recurrence, and one patient had successful removal of the tumor with preservation of all functions of the cranial, nerves, including the facial nerve. Conclusion: Vestibular schwannomas in children are very uncommon. It is likely that it is the first manifestation of NF2, but it may also be a variant of sporadic vestibular schwannomas. A presentation of three cases and a review of 36 other cases in the literature demonstrates how the presentationis different from adult sporadic vestibular schwannomas and NF2 because itlacks primary audiological symptoms. The study also provides evidence of non-NF2 vestibular schwannomas presenting in children and suggests that it is likely that these are a variant of unilateral sporadic vestibular schwannomas. The search for the features of NF2 in these cases remains mandatory.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 20:13:23