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Titolo:
Improved detection of differential information-processing speed deficits between two disease-course types of multiple sclerosis
Autore:
Snyder, PJ; Cappelleri, JC; Archibald, CJ; Fisk, JD;
Indirizzi:
Pfizer Inc, Pfizer Global Res & Dev, Dept Clin Res, Groton, CT 06340 USA Pfizer Inc Groton CT USA 06340 & Dev, Dept Clin Res, Groton, CT 06340 USA Univ Connecticut, Dept Psychol, Storrs, CT USA Univ Connecticut Storrs CTUSA Connecticut, Dept Psychol, Storrs, CT USA Pfizer Inc, Pfizer Global Res & Dev, Clin Biostat & Reporting, Groton, CT 06340 USA Pfizer Inc Groton CT USA 06340 Biostat & Reporting, Groton, CT 06340 USA Foothills Med Ctr, Calgary, AB, Canada Foothills Med Ctr Calgary AB Canada othills Med Ctr, Calgary, AB, Canada Dalhousie Univ, Dept Psychol, Halifax, NS, Canada Dalhousie Univ Halifax NS Canada Univ, Dept Psychol, Halifax, NS, Canada Queen Elizabeth II Hlth Sci Ctr, Halifax, NS, Canada Queen Elizabeth II Hlth Sci Ctr Halifax NS Canada r, Halifax, NS, Canada
Titolo Testata:
NEUROPSYCHOLOGY
fascicolo: 4, volume: 15, anno: 2001,
pagine: 617 - 625
SICI:
0894-4105(200110)15:4<617:IDODIS>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
COGNITIVE IMPAIRMENT; FUNCTIONAL COMPOSITE; DISABILITY; ATTENTION; CRITERIA; PATTERNS; TASK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Snyder, PJ Pfizer Inc, Pfizer Global Res & Dev, Dept Clin Res, Bldg 260,Eastern PointRd, Groton, CT 06340 USA Pfizer Inc Bldg 260,Eastern Point Rd Groton CT USA 06340 40 USA
Citazione:
P.J. Snyder et al., "Improved detection of differential information-processing speed deficits between two disease-course types of multiple sclerosis", NEUROPSYCHL, 15(4), 2001, pp. 617-625

Abstract

Patients with multiple sclerosis (MS) frequently demonstrate impairments of information-processing speed (IPS) on measures such as the Paced AuditorySerial Addition Test (PASAT, D. M. A. Gronwall, 1977). The authors have previously shown that their new PASAT scoring method (mean dyad score) is better correlated in comparison with more traditional PASAT scoring method(s),with magnetic resonance imaging measurement of the total area (mm(2)) of white-matter sclerotic lesions (P. J. Snyder & J. C. Cappelleri, 2001). The present study reports that the mean dyad score discriminated 20 relapsing-remitting MS (RRMS) patients from 15 secondary-progressive MS (SPMS) patients noticeably better than did the standard scoring method(s). Mean dyad scores < 4.13 classified patients as having SPMS with 73% accuracy (sensitivity), whereas scores greater than or equal to 4.13 classified patients as having RRMS with 80% accuracy (specificity).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 05:43:10