Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Salt-loading increases vasopressin and vasopressin 1b receptor mRNA in thehypothalamus and choroid plexus
Autore:
Zemo, DA; McCabe, JT;
Indirizzi:
Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Anat Physiol &Genet, Bethesda, MD 20814 USA Uniformed Serv Univ Hlth Sci Bethesda MD USA20814 Bethesda, MD 20814 USA
Titolo Testata:
NEUROPEPTIDES
fascicolo: 3-4, volume: 35, anno: 2001,
pagine: 181 - 188
SICI:
0143-4179(200106/08)35:3-4<181:SIVAV1>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER RIBONUCLEIC-ACIDS; VASOGENIC BRAIN EDEMA; ARGININE-VASOPRESSIN; CEREBROSPINAL-FLUID; SUPRAOPTIC NUCLEUS; VOLUME REGULATION; NA+/H+ EXCHANGE; CHRONIC STRESS; V1A RECEPTOR; BLOOD-FLOW;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
68
Recensione:
Indirizzi per estratti:
Indirizzo: McCabe, JT Uniformed Serv Univ Hlth Sci, F Edward Hebert Sch Med, Dept Anat Physiol &Genet, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA Uniformed Serv Univ Hlth Sci 4301 Jones Bridge Rd Bethesda MD USA 20814
Citazione:
D.A. Zemo e J.T. McCabe, "Salt-loading increases vasopressin and vasopressin 1b receptor mRNA in thehypothalamus and choroid plexus", NEUROPEPTID, 35(3-4), 2001, pp. 181-188

Abstract

The choroid plexus plays a pivotal role in the production of cerebrospinalfluid (CSF). Messenger RNA (mRNA) transcripts encoding arginine vasopressin (AVP) and the vasopressin 1b receptor (V1bR) are found in various structures of the central nervous system, including the choroid plexus. The present study measured AVP and V1bR mRNA production in response to plasma hyperosmolality. Compared to rats maintained on water, 2% salt-drinking rats had increased levels of AVP and V1bR mRNAs in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus and in the choroid plexus. The increase in V1bR mRNA in the SON and PVN as a result of plasma hyperosmolality may reflect changes in receptor production that, in turn, have a role in AVP autoregulation of hypothalamic magnocellular neurons. The increase of AVPand V1bR mRNAs in the choroid plexus further shows the involvement of AVP in the regulation of brain water content and cerebral edema. (C) 2001 Harcourt Publishers Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:06:18