Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Urinary thioether excretion and erythrocyte glutathione S-transferase activities in smokers and patients with squamous-cell laryngeal cancer
Autore:
Kuralay, F; Yildiz, T;
Indirizzi:
Dokuz Eylul Univ, Sch Med, Dept Biochem, TR-35340 Izmir, Turkey Dokuz Eylul Univ Izmir Turkey TR-35340 t Biochem, TR-35340 Izmir, Turkey Celal Bayar Univ, Sch Med, Dept Otorhinolaryngol, Manisa, Turkey Celal Bayar Univ Manisa Turkey d, Dept Otorhinolaryngol, Manisa, Turkey
Titolo Testata:
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A
fascicolo: 6, volume: 64, anno: 2001,
pagine: 447 - 452
SICI:
1528-7394(20011123)64:6<447:UTEAEG>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
CIGARETTE SMOKERS; EXPOSURE; MUTAGENICITY; CARCINOMAS; CHILDREN; SMOKING; RISK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Kuralay, F Dokuz Eylul Univ, Sch Med, Dept Biochem, TR-35340 Izmir, TurkeyDokuz Eylul Univ Izmir Turkey TR-35340 TR-35340 Izmir, Turkey
Citazione:
F. Kuralay e T. Yildiz, "Urinary thioether excretion and erythrocyte glutathione S-transferase activities in smokers and patients with squamous-cell laryngeal cancer", J TOX E H A, 64(6), 2001, pp. 447-452

Abstract

Various biomarkers exist for assessment of exposure to cigarette smoke. The aim of this study is to evaluate whether the urinary thioethers UT) and erythrocyte glutathione S-transferase (GST) enzyme activities can be used asa biomarker or indicator of a higher risk of laryngeal cancer among smokers. In the present study, the concentration of UT and erythrocyte CST activities were measured in a sample of 84 subjects: controls, smokers, and smokers with squamous-cell carcinoma of the larynx (SLC). For this study, cases were restricted to men, since the number of women was not sufficient for statistical comparisons. Smoking significantly increased UT levels without a marked change in CST activity, However, in SLC smoking patients both UT levels and CST activity were significantly elevated. The use of nonspecific UTlevels with CST activity determination seems to be a reliable indicator for the presence of laryngeal cancer in smokers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:20:34