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Titolo:
Typical and atypical Carney's triad presenting with malignant hypertensionand papilledema
Autore:
Valverde, K; Henderson, M; Smith, CR; Tallett, S; Chan, HSL;
Indirizzi:
Univ Toronto, Hosp Sick Children, Div Hematol Oncol, Toronto, ON M5G 1X8, Canada Univ Toronto Toronto ON Canada M5G 1X8 Oncol, Toronto, ON M5G 1X8, Canada
Titolo Testata:
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
fascicolo: 8, volume: 23, anno: 2001,
pagine: 519 - 524
SICI:
1077-4114(200111)23:8<519:TAACTP>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXTRA-ADRENAL PARAGANGLIOMA; GASTRIC EPITHELIOID LEIOMYOSARCOMA; PULMONARY CHONDROMA; TUMORS;
Keywords:
Carney's triad; gastric stromal sarcoma; pulmonary chondroma; extraadrenal paraganglioma; malignant hypertension; papilledema; benign intracranial hypertension; iron-deficiency anemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Chan, HSL Univ Toronto, Hosp Sick Children, Div Hematol Oncol, 555 Univ Ave, Toronto, ON M5G 1X8, Canada Univ Toronto 555 Univ Ave Toronto ON Canada M5G 1X8 1X8, Canada
Citazione:
K. Valverde et al., "Typical and atypical Carney's triad presenting with malignant hypertensionand papilledema", J PED H ONC, 23(8), 2001, pp. 519-524

Abstract

This report encourages clinicians to consider a diagnosis of Carney's triad in patients with multifocal gastric stromal sarcoma, extraadrenal paraganglioma (predominantly mediastinal), or pulmonary chondroma. The authors conducted a retrospective 20-year survey at the Hospital for Sick Children andidentified two children with Carney's triad. One child, presenting atypically with papilledema and fundal hemorrhages from malignant hypertension andbenign intracranial hypertension from chronic iron-deficiency anemia, is the second patient ever to date be described with the complete Carney's triad of neoplasms at diagnosis. Another child presented more typically with gastric stromal sarcoma and pulmonary chondroma without paraganglioma. Carney's triad is a rare differential diagnosis for "idiopathic" hypertension or iron-deficiency anemia from chronic gastrointestinal bleeding. If missed, patients with Carney's triad may have the debilitating physical and mental consequences of chronic iron deficiency and may die of untreated prolonged hypertension and metastatic leiomyosarcoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 09:57:04