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Titolo:
Advances in fetal surgery
Autore:
MacKenzie, TC; Adzick, NS;
Indirizzi:
Childrens Hosp Philadelphia, Ctr FetalDiag & Treatment, Philadelphia, PA 19104 USA Childrens Hosp Philadelphia Philadelphia PA USA 19104 lphia, PA 19104 USA
Titolo Testata:
JOURNAL OF INTENSIVE CARE MEDICINE
fascicolo: 6, volume: 16, anno: 2001,
pagine: 251 - 262
SICI:
0885-0666(200111/12)16:6<251:AIFS>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONGENITAL DIAPHRAGMATIC-HERNIA; CYSTIC ADENOMATOID MALFORMATION; SEVERE COMBINED IMMUNODEFICIENCY; INTRAPARTUM TREATMENT PROCEDURE; POSTERIOR URETHRAL VALVES; IN-UTERO TRANSPLANTATION; PRENATAL MRI EVALUATION; TO-HEAD RATIO; SACROCOCCYGEAL TERATOMA; SPINA-BIFIDA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
82
Recensione:
Indirizzi per estratti:
Indirizzo: Adzick, NS Childrens Hosp Philadelphia, Ctr FetalDiag & Treatment, 34th St& Civ Ctr Blvd, Philadelphia, PA 19104 USA Childrens Hosp Philadelphia 34th St & Civ Ctr Blvd Philadelphia PA USA 19104
Citazione:
T.C. MacKenzie e N.S. Adzick, "Advances in fetal surgery", J INTENS C, 16(6), 2001, pp. 251-262

Abstract

Advances in prenatal screening and diagnosis, combined with an understanding of the pathophysiology of congenital anomalies, have brought incredible impetus to the field of fetal surgery. Identification of fetal anomalies can lead to counseling of the affected family so that informed decisions can be made on how to proceed with the pregnancy. Counseling may lead to pregnancy termination, changes in the timing or mode of delivery, and, in select cases, prenatal intervention. Open fetal surgery may be considered in severe cases of congenital diaphragmatic hernia, congenital chest lesions, sacrococcygeal teratoma, urinary tract obstruction, and myelomeningocele. The exutero intrapartum treatment procedure may be lifesaving for fetuses with giant neck masses. Finally, fetoscopic surgery may be offered for select cases of twin-twin transfusion syndrome and twin reversed arterial perfusion sequence. Fetal intervention in all of these cases depends on a team approach to the patient and on the objective comparison of outcomes with and without fetal therapy In the future, further understanding of the genetic basis of congenital diseases may enable minimally invasive treatments such as stem cell transplantation or gene therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 12:07:08