Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Atypical rotavirus identified from young children with diarrhoea in South Africa
Autore:
Sebata, T; Steele, AD;
Indirizzi:
MRC, MEDUNSA, Diarrhoeal Pathogens Res Unit, ZA-0204 Medunsa, South AfricaMRC Medunsa South Africa ZA-0204 Res Unit, ZA-0204 Medunsa, South Africa
Titolo Testata:
JOURNAL OF HEALTH POPULATION AND NUTRITION
fascicolo: 3, volume: 19, anno: 2001,
pagine: 199 - 203
SICI:
1606-0997(200109)19:3<199:ARIFYC>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
MONOCLONAL-ANTIBODIES; BLACK INFANTS; ANTIGENS;
Keywords:
rotavirus; diarrhoea; infantile; South Africa;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Steele, AD MRC, MEDUNSA, Diarrhoeal Pathogens Res Unit, POB 173, ZA-0204 Medunsa, South Africa MRC POB 173 Medunsa South Africa ZA-0204 Medunsa, South Africa
Citazione:
T. Sebata e A.D. Steele, "Atypical rotavirus identified from young children with diarrhoea in South Africa", J HEALTH PO, 19(3), 2001, pp. 199-203

Abstract

The study was undertaken for antigenic characterization of rotavirus strains isolated from South African children. During July 1996-July 1997, an epidemiological surveillance of rotavirus-associated gastroenteritis was carried out in Pretoria and Gauteng provinces. In total, 1,229 diarrhoeal faecalsamples were collected from a pathology laboratory. Of 389 (32%) rotavirusstrains detected, most (97%) were group A rotaviruses by serological assay. However, 12 rotavirus strains identified did not apparently carry the common group A-specific antigen as determined by both commercial and monoclonal antibody-based ELISAs. Electrophoretic analysis of the viral RNA genome revealed that these strains shared a common electropherotype and that this resembled the group A rotavirus constellation of RNA segments. Furthermore, the conserved terminal sequences of the group A VP6 and VP7 genes could notbe targeted by standard reverse transcriptase-polymerase chain reaction with a routine set of primers to the VP6 or VP7 genes. These strains present an interesting phenotypic variation of the recognized rotaviruses and warrant further characterization.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 12:52:31