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Titolo:
Cyclophosphamide and related anticancer drugs
Autore:
Baumann, F; Preiss, R;
Indirizzi:
Univ Leipzig, Inst Clin Pharmacol, D-04107 Leipzig, Germany Univ Leipzig Leipzig Germany D-04107 Pharmacol, D-04107 Leipzig, Germany
Titolo Testata:
JOURNAL OF CHROMATOGRAPHY B
fascicolo: 1-2, volume: 764, anno: 2001,
pagine: 173 - 192
SICI:
1387-2273(20011125)764:1-2<173:CARAD>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; CAPILLARY GAS-CHROMATOGRAPHY; NUCLEAR-MAGNETIC-RESONANCE; TANDEM MASS-SPECTROMETRY; ELECTRON-CAPTURE DETECTION; HUMAN LIVER-MICROSOMES; NITROGEN-PHOSPHORUS; DECHLOROETHYLATED METABOLITES; HUMAN-PLASMA; ISOPHOSPHORAMIDE MUSTARD;
Keywords:
reviews; oxazaphosphorines; cyclophosphamide; ifosfamide; trofosfamide;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
158
Recensione:
Indirizzi per estratti:
Indirizzo: Baumann, F Univ Leipzig, Inst Clin Pharmacol, Hartelstr 16-18, D-04107 Leipzig, Germany Univ Leipzig Hartelstr 16-18 Leipzig Germany D-04107 , Germany
Citazione:
F. Baumann e R. Preiss, "Cyclophosphamide and related anticancer drugs", J CHROMAT B, 764(1-2), 2001, pp. 173-192

Abstract

This article presents an overview of the methods of bioanalysis of oxazaphosphorines, in particular, cyclophosphamide, ifosfamide, and trofosfamide as well as their metabolites. The metabolism of oxazaphosphorines is complexand leads to a large variety of metabolites and therefore the spectrum of methods used is relatively broad. The various methods used are shown in a table and the particularly important assays are described. (C) 2001 ElsevierScience B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 22:02:41