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Titolo:
Chromatographic techniques for the determination of putative dietary anticancer compounds in biological fluids
Autore:
Oliveira, EJ; Watson, DG;
Indirizzi:
Univ Strathclyde, Strathclyde Inst Biomed Sci, Dept Pharmaceut Sci, Glasgow G4 0NR, Lanark, Scotland Univ Strathclyde Glasgow Lanark Scotland G4 0NR G4 0NR, Lanark, Scotland
Titolo Testata:
JOURNAL OF CHROMATOGRAPHY B
fascicolo: 1-2, volume: 764, anno: 2001,
pagine: 3 - 25
SICI:
1387-2273(20011125)764:1-2<3:CTFTDO>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; IONIZATION MASS-SPECTROMETRY; ELECTROKINETIC CAPILLARY CHROMATOGRAPHY; COULOMETRIC ELECTROCHEMICAL DETECTION; SOLID-PHASE EXTRACTION; C-30 STATIONARY PHASES; HUMAN PLASMA; ALPHA-TOCOPHEROL; ASCORBIC-ACID; BETA-CAROTENE;
Keywords:
reviews; flavonoids; phytoestrogens; carotenoids; vitamin E; retinoids; ascorbic acid;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
98
Recensione:
Indirizzi per estratti:
Indirizzo: Watson, DG Univ Strathclyde, Strathclyde Inst Biomed Sci, Dept Pharmaceut Sci, 27 Taylor St, Glasgow G4 0NR, Lanark, Scotland Univ Strathclyde 27 Taylor St Glasgow Lanark Scotland G4 0NR nd
Citazione:
E.J. Oliveira e D.G. Watson, "Chromatographic techniques for the determination of putative dietary anticancer compounds in biological fluids", J CHROMAT B, 764(1-2), 2001, pp. 3-25

Abstract

Although a great number of papers demonstrate an association between high intake of fruits and vegetables and reduced risk of certain types of cancer, the epidemiological evidence is not conclusive. The identification and quantification of specific dietary anticancer compounds in plasma, urine and tissues is an important aspect of this research. We surveyed the recent literature for original papers which involved the use of separation techniquesfor the detection and quantification in biological fluids and tissues of putative anticancer compounds which are present in the diet. The compounds included in this review are flavonoids, phytoestrogens, carotenoids, retinoids, vitamin E and ascorbic acid. The review covers papers published in the last 3 years. For each class of compounds we discuss the sample preparation, chromatographic conditions, and validation of the methods used, in order to identify current trends in the bioanalysis of each class of these substances. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 06:35:44