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Titolo:
Impact of HIV infection on mortality in a cohort of injection drug users
Autore:
Tyndall, MW; Craib, KJP; Currie, S; Li, K; OShaughnessy, MV; Schechter, MT;
Indirizzi:
St Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, Vancouver, BC V6Z1Y6, Canada St Pauls Hosp Vancouver BC Canada V6Z 1Y6 S, Vancouver, BC V6Z1Y6, Canada Univ British Columbia, Dept Hlth Care & Epidemiol, Vancouver, BC V6T 1W5, Canada Univ British Columbia Vancouver BC Canada V6T 1W5 ver, BC V6T 1W5, Canada Univ British Columbia, Dept Med, Vancouver, BC V6T 1W5, Canada Univ British Columbia Vancouver BC Canada V6T 1W5 ver, BC V6T 1W5, Canada Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC V6T 1W5, Canada Univ British Columbia Vancouver BC Canada V6T 1W5 ver, BC V6T 1W5, Canada
Titolo Testata:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
fascicolo: 4, volume: 28, anno: 2001,
pagine: 351 - 357
SICI:
1525-4135(200112)28:4<351:IOHIOM>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIRETROVIRAL THERAPY; COCAINE USE; SOCIOECONOMIC-STATUS; METHADONE TREATMENT; IMPROVED SURVIVAL; UNITED-STATES; YOUNG-ADULTS; OVERDOSE; DEATHS; AIDS;
Keywords:
mortality; overdose; HIV; injection drug use;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Tyndall, MW St Pauls Hosp, British Columbia Ctr Excellence HIV AIDS, 611-1083 Burrard St, Vancouver, BC V6Z 1Y6, Canada St Pauls Hosp 611-1083 Burrard St Vancouver BC Canada V6Z 1Y6
Citazione:
M.W. Tyndall et al., "Impact of HIV infection on mortality in a cohort of injection drug users", J ACQ IMM D, 28(4), 2001, pp. 351-357

Abstract

The prevalence of HIV has been rising among injection drug users (IDUs) and AIDS is now an important cause of death among that population. We trackedmortality and recorded detailed causes of death in the Vancouver InjectionDrug Users Study (VIDUS). This is an open cohort of over 1,400 active IDUsthat began in May 1996. At enrollment and at semiannual follow-up visits, a trained interviewer administers a detailed semistructured questionnaire. Mortality was recorded during follow-up and detailed causes of death were collected from coroner's reports, hospital records, and the provincial (British Columbia) registry. Causes of death were obtained on 125 participants. Overall, the leading cause of death was overdose accounting for 25% of deaths among HIV-positive participants and 42% among HIV-negative participants. Of the 65 deaths among HIV-positive individuals, 22 (34%) were HIV related. Mortality was associated with older age (adjusted hazards ratio [AHR], 1.03 per year), HIV positivity (AHR, 2.67), injection cocaine use (AHR, 2.23)and methadone treatment (AHR, 0.47). The high rate of HIV in this population has added significantly to the burden of illness and death in this marginalized population.

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Documento generato il 19/02/20 alle ore 21:05:33