Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The elevation of natural killer cell activity induced by laughter in a crossover designed study
Autore:
Takahashi, K; Iwase, M; Yamashita, K; Tatsumoto, Y; Ue, H; Kuratsune, H; Shimizu, A; Takeda, M;
Indirizzi:
Osaka Univ, Dept Clin Neurosci Psychiat, Grad Sch Med, Suita, Osaka 5650871, Japan Osaka Univ Suita Osaka Japan 5650871 Sch Med, Suita, Osaka 5650871, Japan Osaka Univ, Grad Sch Med, Dept Hematol & Oncol, Osaka, Japan Osaka Univ Osaka Japan Grad Sch Med, Dept Hematol & Oncol, Osaka, Japan Kansai Univ Welf Sci, Fac Social Welf, Osaka, Japan Kansai Univ Welf Sci Osaka Japan elf Sci, Fac Social Welf, Osaka, Japan
Titolo Testata:
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
fascicolo: 6, volume: 8, anno: 2001,
pagine: 645 - 650
SICI:
1107-3756(200112)8:6<645:TEONKC>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC FATIGUE SYNDROME; MIRTHFUL LAUGHTER; STRESS; BRAIN; EXPRESSION;
Keywords:
laughter; natural killer cell activity; crossover design; electromyogram; pleasantness;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Takahashi, K Osaka Univ, Dept Clin Neurosci Psychiat, Grad Sch Med, 2-2 Yamadaoka,D3, Suita, Osaka 5650871, Japan Osaka Univ 2-2 Yamadaoka,D3 Suita Osaka Japan 5650871 , Japan
Citazione:
K. Takahashi et al., "The elevation of natural killer cell activity induced by laughter in a crossover designed study", INT J MOL M, 8(6), 2001, pp. 645-650

Abstract

The elevation of natural killer cell activity (NKCA) by laughter was not confirmed due to incomplete methodology of previous studies although positive emotion is believed to be favorable for health. To verify NKCA elevation by laughter in a crossover design, we measured NKCA before and after watching films, presenting, 75-min comic film and nonemotional control film at different days to the same 21 healthy male subjects. Electromyogram of left major zygomatic muscle was obtained during the films to quantify the magnitude of laughter as an index of emotional expression. As indices of emotionalexperience, the self-rated pleasantness of the comic film and mood state before and after film were measured using visual analogue scale and Profilesof Mood State (POMS), respectively. The comic film significantly elevated NKCA (26.5-29.4%, p <0.05), whereas the control film did not (27.1-24.8%, not significant). This is the first study to demonstrate NKCA elevation by laughter in a crossover designed study. To examine the contribution of experiential and expressive aspects of laughter to NKCA elevation, correlation of NKCA elevation with the self-rated pleasantness, mood scores before and after comic film and the magnitude of laughter was statistically tested. We found that NKCA elevation was negatively correlated with the scores of negative mood scales of POMS while NKCA elevation had no significant correlation with self-rated pleasantness and the magnitude of laughter. Further groupanalysis revealed that high scores of depression and anger-hostility suppressed NKCA elevation by laughter. We also found that NKCA before and after comic film had tendency of correlation with self-rated pleasantness of the comic film while NKCA had no correlation with the magnitude of laughter. These findings suggest that NKCA elevation and NKCA before and after comic film seem to be related with the experiential aspects of laughter rather thanwith the expressive aspects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:24:46