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Titolo:
Roles of nodal-lefty regulatory loops in embryonic patterning of vertebrates
Autore:
Juan, H; Hamada, H;
Indirizzi:
Osaka Univ, Inst Mol & Cellular Biol, Suita, Osaka 5650871, Japan Osaka Univ Suita Osaka Japan 5650871 ar Biol, Suita, Osaka 5650871, Japan
Titolo Testata:
GENES TO CELLS
fascicolo: 11, volume: 6, anno: 2001,
pagine: 923 - 930
SICI:
1356-9597(200111)6:11<923:RONRLI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
RIGHT ASYMMETRIC EXPRESSION; ANTERIOR PRIMITIVE ENDODERM; TGF-BETA SUPERFAMILY; EARLY MOUSE EMBRYO; NEURALIZING ACTIVITY; MESODERM INDUCTION; SIGNALING PATHWAY; AXIS DEVELOPMENT; GENE; GASTRULATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
60
Recensione:
Indirizzi per estratti:
Indirizzo: Hamada, H Osaka Univ, Inst Mol & Cellular Biol, 1-3 Yamada Oka, Suita, Osaka 5650871, Japan Osaka Univ 1-3 Yamada Oka Suita Osaka Japan 5650871 50871, Japan
Citazione:
H. Juan e H. Hamada, "Roles of nodal-lefty regulatory loops in embryonic patterning of vertebrates", GENES CELLS, 6(11), 2001, pp. 923-930

Abstract

Nodal is a signalling molecule that belongs to the transforming growth factor-beta superfamily of proteins, and Lefty proteins are antagonists of Nodal signalling. The nodal and lefty genes form positive and negative regulatory loops that resemble the reaction-diffusion system. As a pair, these genes control various events of vertebrate embryonic patterning, including left-right specification and mesoderm formation. In this review, we will focuson recent studies that have addressed the roles of nodal and lefty in mouse development.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 00:35:38