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Titolo:
Quantitative computed tomography assessment of lung structure and functionin pulmonary emphysema
Autore:
Madani, A; Keyzer, C; Gevenois, PA;
Indirizzi:
Free Univ Brussels, Hop Erasme, Dept Radiol, B-1070 Brussels, Belgium FreeUniv Brussels Brussels Belgium B-1070 iol, B-1070 Brussels, Belgium
Titolo Testata:
EUROPEAN RESPIRATORY JOURNAL
fascicolo: 4, volume: 18, anno: 2001,
pagine: 720 - 730
SICI:
0903-1936(200110)18:4<720:QCTAOL>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
VOLUME-REDUCTION SURGERY; HIGH-RESOLUTION CT; SPIROMETRICALLY CONTROLLED CT; THIN-SECTION CT; FUNCTION TESTS; MACROSCOPIC MORPHOMETRY; MICROSCOPIC MORPHOMETRY; REGIONAL DISTRIBUTION; DENSITY MASK; HELICAL CT;
Keywords:
computed tomography; diagnosis; emphysema;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
78
Recensione:
Indirizzi per estratti:
Indirizzo: Gevenois, PA Free Univ Brussels, Hop Erasme, Dept Radiol, 808 Route Lennik, B-1070 Brussels, Belgium Free Univ Brussels 808 Route Lennik Brussels Belgium B-1070
Citazione:
A. Madani et al., "Quantitative computed tomography assessment of lung structure and functionin pulmonary emphysema", EUR RESP J, 18(4), 2001, pp. 720-730

Abstract

Accurate diagnosis and quantification of pulmonary emphysema during life is important to understand the natural history of the disease, to assess theextent of the disease, and to evaluate and follow-up therapeutic interventions. Since pulmonary emphysema is defined through pathological criteria, new methods of diagnosis and quantification should be validated by comparisons against histological references. Recent studies have addressed the capability of computed tomography (CT) to quantify pulmonary emphysema accurately. The studies reviewed in this article have been based on CT scans obtained after deep inspiration or expiration, on subjective visual grading and on objective measurements of attenuation values. Especially dedicated software was used for this purpose, which provided numerical data, on both two- and three-dimensional approaches, andcompared CT data with pulmonary function tests. More recently, fractal and textural analyses were applied to computed tomography scans to assess the presence, the extent, and the types of emphysema. Quantitative computed tomography has already been used in patient selection for surgical treatment of pulmonary emphysema and in pharmacotherapeutical trials. However, despite numerous and extensive studies, this technique has not yet been standardized and important questions about how best to usecomputed tomography for the quantification of pulmonary emphysema are still unsolved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 19:16:38