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Titolo:
Inspiratory flow limitation during sleep in pre-eclampsia: comparison withnormal pregnant and nonpregnant women
Autore:
Connolly, G; Razak, ARA; Hayanga, A; Russell, A; McKenna, P; McNicholas, WT;
Indirizzi:
St Vincent Univ Hosp, Dept Resp Med, Resp Sleep Disorders Unit, Dublin 4, Ireland St Vincent Univ Hosp Dublin Ireland 4 Disorders Unit, Dublin 4, Ireland Rotunda Hosp, Dept Obstet, Dublin, Ireland Rotunda Hosp Dublin IrelandRotunda Hosp, Dept Obstet, Dublin, Ireland Rotunda Hosp, Dept Gynaecol, Dublin, Ireland Rotunda Hosp Dublin Ireland otunda Hosp, Dept Gynaecol, Dublin, Ireland
Titolo Testata:
EUROPEAN RESPIRATORY JOURNAL
fascicolo: 4, volume: 18, anno: 2001,
pagine: 672 - 676
SICI:
0903-1936(200110)18:4<672:IFLDSI>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMBULATORY BLOOD-PRESSURE; APNEA SYNDROME; PREECLAMPSIA; HYPERTENSION; POLYSOMNOGRAPHY; TITRATION; SYSTEM;
Keywords:
hypertension; inspiratory flow limitation; pre-eclampsia; pregnancy; sleep apnoea;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: McNicholas, WT St Vincent Univ Hosp, Dept Resp Med, Resp Sleep Disorders Unit, Elm Pk, Dublin 4, Ireland St Vincent Univ Hosp Elm Pk Dublin Ireland 4 in 4, Ireland
Citazione:
G. Connolly et al., "Inspiratory flow limitation during sleep in pre-eclampsia: comparison withnormal pregnant and nonpregnant women", EUR RESP J, 18(4), 2001, pp. 672-676

Abstract

Self-reported snoring is common in pregnancy, particularly in females withpre-eclampsia. The prevalence of inspiratory flow limitation during sleep in preeclamptic females was objectively assessed and compared with normal pregnant and nonpregnant females. Fifteen females with pre-eclampsia were compared to 15 females from each of the three trimesters of pregnancy, as well as to 15 matched nonpregnant control females (total study population, 75 subjects). All subjects had overnight monitoring of respiration, oxygen saturation, and blood pressure (BP). No group had evidence of a clinically significant sleep apnoea syndrome, but patients with pre-eclampsia spent substantially more time (31 +/-8.4%, of sleep period time, mean SD) with evidence of inspiratory flow limitation compared to 15.5 +/-2.3% in third trimester subjects and <5% in the other three groups (p=0.001). In the majority of preeclamptics, the pattern of flow limitation was of prolonged episodes lasting several minutes without associated oxygen desaturation. As expected, systolic and diastolic BPs were significantly higher in the pre-eclamptic group (p<0.001), but all groups showed a significant fall (p less than or equal to0.05) in BP during sleep. Inspiratory flow limitation is common during sleep in patients with pre-eclampsia, which may have implications for the pathophysiology and treatment of this disorder.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 12:52:35