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Titolo:
Infectious complications and antibiotic use in renal transplant recipientsduring a 1-year follow-up
Autore:
Maraha, B; Bonten, H; van Hooff, H; Fiolet, H; Buiting, AG; Stobberingh, EE;
Indirizzi:
St Elizabeth Hosp, Dept Med Microbiol, NL-5000 AS Tilburg, Netherlands St Elizabeth Hosp Tilburg Netherlands NL-5000 AS AS Tilburg, Netherlands Univ Utrecht, Med Ctr, Dept Internal Med, Div Infect Dis & AIDS, Utrecht, Netherlands Univ Utrecht Utrecht Netherlands nfect Dis & AIDS, Utrecht, Netherlands Univ Hosp, Dept Med Microbiol, Maastricht, Netherlands Univ Hosp Maastricht Netherlands Med Microbiol, Maastricht, Netherlands Univ Hosp, Dept Internal Med, Maastricht, Netherlands Univ Hosp Maastricht Netherlands Internal Med, Maastricht, Netherlands
Titolo Testata:
CLINICAL MICROBIOLOGY AND INFECTION
fascicolo: 11, volume: 7, anno: 2001,
pagine: 619 - 625
SICI:
1198-743X(200111)7:11<619:ICAAUI>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY-TRACT INFECTIONS; WOUND-INFECTION; PROPHYLAXIS;
Keywords:
renal transplantation; infectious complications; antibiotic use;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Maraha, B St Elizabeth Hosp, Dept Med Microbiol, POB 747, NL-5000 AS Tilburg, Netherlands St Elizabeth Hosp POB 747 Tilburg Netherlands NL-5000 AS rlands
Citazione:
B. Maraha et al., "Infectious complications and antibiotic use in renal transplant recipientsduring a 1-year follow-up", CL MICRO IN, 7(11), 2001, pp. 619-625

Abstract

Objective To evaluate infectious complications and antibiotic use in 192 renal transplant recipients. Methods Infectious complications and antibiotic use were monitored in all patients receiving renal transplantation at our center from 1992 to 1997. Risk factors for infectious complications were evaluated. Transplants and patient survival were monitored. The follow-up period was 1 year. Results One-hundred and ninety-two patients received renal transplants during the study period. The mean duration of urethral catheterisation after transplantation was 10.5 days (SD=5). Seventy-one per cent (n=137) of patients had at least one infectious episode. In all, 284 infectious episodes were monitored. The most frequent infections were: urinary tract infections 61%, respiratory tract infections 8%, intra-abdominal infections 7%, and cytomegalovirus infection 8%. Escherichia coli and Enterococcus faecalis were the most frequently isolated microorganisms. Seventy-four per cent (n=142) of patients received 314 antimicrobial courses (284 for therapy, and 30 for prophylaxis). Female gender and duration of urethral catheterisation were risk factors for urinary tract infection. Cytomegalovirus reactivation was associated with acute graft rejection and additional immunosuppressive therapy. Overall mortality was 4%. Infection-related mortality was 2.6%. Mortality was associated with Enterobacteriaceae in three patients, with Pseudomonas aeroginosa in one patient and with Enterococcus faecalis in one patient. Conclusions The incidence of infectious complications remains high in renal transplant recipients. Most cases of mortality were associated with infections. Early removal of the urethral catheter to reduce the risk of urinarytract infections is recommended.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 09:41:12