Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Dipyridamole stress echocardiography vs dipyridamole sestamibi scintigraphy for diagnosing coronary artery disease in left bundle-branch block
Autore:
Vigna, C; Stanislao, M; De Rito, V; Russo, A; Natali, R; Santoro, T; Loperfido, F;
Indirizzi:
Univ Sacred Heart, Ist Cardiol, Complesso Integrato Columbus, I-00168 Rome, Italy Univ Sacred Heart Rome Italy I-00168 grato Columbus, I-00168 Rome, Italy IRCCS, Casa Sollievo Sofferenza Hosp, Dept Cardiol, Rome, Italy IRCCS Rome Italy sa Sollievo Sofferenza Hosp, Dept Cardiol, Rome, Italy
Titolo Testata:
CHEST
fascicolo: 5, volume: 120, anno: 2001,
pagine: 1534 - 1539
SICI:
0012-3692(200111)120:5<1534:DSEVDS>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
EMISSION COMPUTED-TOMOGRAPHY; DOBUTAMINE STRESS; MYOCARDIAL PERFUSION; FLOW RESERVE; TL-201; EXERCISE; ADENOSINE;
Keywords:
left bundle-branch block; myocardial perfusion scintigraphy; stress echocardiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Loperfido, F Univ Sacred Heart, Ist Cardiol, Complesso Integrato Columbus,Via G Moscati 31-33, I-00168 Rome, Italy Univ Sacred Heart Via G Moscati 31-33 Rome Italy I-00168 aly
Citazione:
C. Vigna et al., "Dipyridamole stress echocardiography vs dipyridamole sestamibi scintigraphy for diagnosing coronary artery disease in left bundle-branch block", CHEST, 120(5), 2001, pp. 1534-1539

Abstract

Study objectives: To evaluate dipyridamole stress echocardiography (DSE) for predicting coronary artery diseases (CADS) in patients with complete left bundle-branch block (LBBB). Design: Comparison of DSE and dipyridamole sestamibi myocardial perfusion scintigraphy (sestamibi). Setting: Tertiary-care cardiac referral center. Patients: Fifty-four consecutive patients (26 men; mean [+/- SD] age, 59 +/-7 years) with complete LBBB (14 patients with left ventricular [LV] dilatation) and intermediate probability of CAD. Methods: Simultaneous single photon emission CT scan (20 mCi technetium Te 99m stress/rest sestamibi) and echocardiography (second harmonic imaging) during a two-step (0.56 to 0.84 mg/kg) dipyridamole infusion protocol. Two sestamibi readings were performed. The first reading considered only those studies with reversible defects (sestamibi-1) to be positive. The second reading considered those studies with any defect (sestamibi-2) to be positive. CAD was defined as a greater than or equal to 50% reduction in diameter in at least one major vessel seenon coronary angiography. Results: CAD was present in 17 patients (31.5%). The global predictive accuracy for CAD was significantly higher for DSE (87.0%) and sestamibi-1 (79.6%) than for sestamibi-2 (57.4%) [p<0.01 vs DSE; p<0.05 vs sestamibi-1]. Nosignificant differences in sensitivity were present, but specificity was significantly higher for DSE (94.6%) and sestamibi-l (81.1%) than for sestamibi-2 (43.2%; p<0.01 vs both the other two tests). Of 14 patients with LV dilatation, 26.8% were falsely positive for CAD (in some cases for posteriordefects) as determined by sestamibi-1 and 64.3% were falsely positive for CAD by sestamibi-2 vs none by DSE. Conclusions: DSE is at least as accurate as dipyridamole sestamibi scintigraphy for predicting CAD in patients with complete LBBB and tends to be more specific in those patients with underlying LV dilatation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 07:57:10