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Titolo:
Structure and functions of classical cadherins
Autore:
Ivanov, DB; Philippova, MP; Tkachuk, VA;
Indirizzi:
Minist Publ Hlth Russian Federat, Russian Cardiol Res & Prod Assoc, Inst Expt Cardiol, Mol Endocrinol Lab, Moscow 121552, Russia Minist Publ Hlth Russian Federat Moscow Russia 121552 cow 121552, Russia
Titolo Testata:
BIOCHEMISTRY-MOSCOW
fascicolo: 10, volume: 66, anno: 2001,
pagine: 1174 - 1186
SICI:
0006-2979(200110)66:10<1174:SAFOCC>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL-CELL-ADHESION; PROTEIN-TYROSINE-PHOSPHATASE; EPIDERMAL GROWTH-FACTOR; SMOOTH-MUSCLE CELLS; LIPOPROTEIN-BINDING-PROTEINS; HUMAN CARCINOMA-CELLS; MOLECULE E-CADHERIN; TRANSFECTED N-CAM; BETA-CATENIN; T-CADHERIN;
Keywords:
cadherins; cell-cell adhesion; morphogenesis; signaling; oncogenesis;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
203
Recensione:
Indirizzi per estratti:
Indirizzo: Tkachuk, VA Minist Publ Hlth Russian Federat, Russian Cardiol Res & Prod Assoc, Inst Expt Cardiol, Mol Endocrinol Lab, 3 Ya Cherepkovskaya Ul 15A, Moscow 121552,Russia Minist Publ Hlth Russian Federat 3 Ya Cherepkovskaya Ul 15A Moscow Russia 121552
Citazione:
D.B. Ivanov et al., "Structure and functions of classical cadherins", BIOCHEM-MOS, 66(10), 2001, pp. 1174-1186

Abstract

Cadherins are a family of membrane receptors that mediate calcium-dependent homophilic cell-cell adhesion. Cadherins play a key role in the regulation of organ and tissue development during embryogenesis. In adult organisms,these proteins are responsible for formation of stable cell-cell junctionsand maintenance of normal tissue structure. Disruption in expression or function of cadherins may cause uncontrolled cell migration and proliferationduring tumor development. This review focuses on the structure and physiological functions of classical cadherins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 11:19:17