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Titolo:
Improved pulmonary adaptation in newborn calves with postnatal acidosis
Autore:
Varga, J; Mester, L; Borzsonyi, L; Lekeux, P; Szenci, O;
Indirizzi:
Szent Istavan Univ, Fac Vet Sci, Dept Obstet & Reprod, H-1400 Budapest, Hungary Szent Istavan Univ Budapest Hungary H-1400 rod, H-1400 Budapest, Hungary Univ Liege, Fac Med Vet, Lab Funct Invest, B-4000 Liege, Belgium Univ Liege Liege Belgium B-4000 Lab Funct Invest, B-4000 Liege, Belgium
Titolo Testata:
VETERINARY JOURNAL
fascicolo: 3, volume: 162, anno: 2001,
pagine: 226 - 232
SICI:
1090-0233(200111)162:3<226:IPAINC>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
GAS-EXCHANGE; BLOOD; CALF; MORTALITY; MECHANICS; CALCIUM; VALUES; PH;
Keywords:
newborn calf; respiratory mechanics; acid-base balance; ionogram;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Varga, J Szent Istavan Univ, Fac Vet Sci, Dept Obstet & Reprod, POB 2, H-1400 Budapest, Hungary Szent Istavan Univ POB 2 Budapest Hungary H-1400 dapest, Hungary
Citazione:
J. Varga et al., "Improved pulmonary adaptation in newborn calves with postnatal acidosis", VET J, 162(3), 2001, pp. 226-232

Abstract

The adaptation of newborn calves to extra-uterine life was evaluated by measuring arterial blood gases, acid-base values, blood ions and lung mechanical function parameters in normal and acidotic calves during the first 24 h. Twenty-seven Holstein Friesian newborn calves were divided into two groups according to their immediate postpartum arterial blood pH values (Group Ablood pH greater than or equal to7.2: normal group; Group B blood pH between 7.2 and 7.0: acidotic group). Pulmonary function parameters were measured and arterial blood samples were analysed for blood gases, acid-base variables and ion content immediately postpartum (within 2 min) and then 6 and 24 h after calving. Lung resistance and maximal difference between pressure maximum and pressure minimum (max Delta Ppl) decreased, while dynamic lung compliance increased significantly in both groups. Immediately post partum the lung resistance and max Delta Ppl were significantly higher in the acidotic group than inthe normal group. The arterial blood pH progressively compensated with time in both groups during the first 24 h and there was no difference in arterial blood pH values between the two groups 6 h after birth. These results showed that the compensation of acidosis was associated with the improvementin lung mechanics and these changes occurred mainly during the first 6 h of life. Moderate to pronounced acidosis did not affect the pulmonary adaptation negatively, although some respiratory mechanics parameters (max Delta Ppl), blood pH and Ca2+ ion concentrations remained significantly differentbetween the normal and acidotic groups at 24 h. This might be the result of overcompensation of acidosis and the interdependence between blood pH andCa2+ concentrations. (C) 2001 Harcourt Publishers Ltd.

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Documento generato il 30/09/20 alle ore 00:40:27