Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Novel HLA-B alleles identified in potential marrow donors: B*3917, B*1405 and B*3528
Autore:
Gourley, IS; Kearns, J; Hou, J; Wu, J; Bassinger, S; Montoya, GD; McKeen, M; Birkos, S; Williams, TM; Kamoun, M;
Indirizzi:
Univ Penn, Dept Pathol & Lab Med, Philadelphia, PA 19035 USA Univ Penn Philadelphia PA USA 19035 & Lab Med, Philadelphia, PA 19035 USA Univ New Mexico, Dept Pathol, Albuquerque, NM 87131 USA Univ New Mexico Albuquerque NM USA 87131 athol, Albuquerque, NM 87131 USA
Titolo Testata:
TISSUE ANTIGENS
fascicolo: 3, volume: 58, anno: 2001,
pagine: 201 - 204
SICI:
0001-2815(200109)58:3<201:NHAIIP>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESOLUTION;
Keywords:
HLA-8; DNA sequencing; bone marrow transplantation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Kamoun, M Univ Penn, Dept Pathol & Lab Med, Philadelphia, PA 19035 USA Univ Penn Philadelphia PA USA 19035 Philadelphia, PA 19035 USA
Citazione:
I.S. Gourley et al., "Novel HLA-B alleles identified in potential marrow donors: B*3917, B*1405 and B*3528", TISSUE ANTI, 58(3), 2001, pp. 201-204

Abstract

Sequence-specific oligonucleotide probe hybridization and sequence-specific primer polymerase chain reaction (PCR) ty-ping of volunteer bone marrow donors suggested the presence of variants of known HLA-B alleles in five individuals. PCR products encompassing HLA-B locus exons 1 through 3 were prepared and subcloned. Three African-American individuals had a novel HLA-B*39allele (B*3917), and another African-American was found to have a novel HLA-B*14 allele (B*1405). In a third individual of Hispanic origin, a novel HLA-B*35 allele (B*3528) was identified. These findings further illustrate the substantial genetic variation present at the HLA-B locus within human populations.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 19:17:41