Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Small airway inflammation in asthma
Autore:
Tulic, MK; Christodoulopoulos, P; Hamid, Q;
Indirizzi:
McGill Univ, Meakins Christie Labs, Montreal, PQ H2X 2P2, Canada McGill Univ Montreal PQ Canada H2X 2P2 Labs, Montreal, PQ H2X 2P2, Canada
Titolo Testata:
RESPIRATORY RESEARCH
fascicolo: 6, volume: 2, anno: 2001,
pagine: 333 - 339
SICI:
1465-993X(2001)2:6<333:SAIIA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RNA EXPRESSION; INHALED FLUTICASONE PROPIONATE; OBSTRUCTIVE PULMONARY-DISEASE; LUNG-TISSUE; NOCTURNAL ASTHMA; PERIPHERAL LUNG; ALVEOLAR TISSUE; CANINE AIRWAYS; FATAL ASTHMA; METHACHOLINE;
Keywords:
allergic inflammation; asthma; peripheral airways; small airways;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
60
Recensione:
Indirizzi per estratti:
Indirizzo: Tulic, MK McGill Univ, Meakins Christie Labs, 3626 St Urbain St, Montreal,PQ H2X 2P2, Canada McGill Univ 3626 St Urbain St Montreal PQ Canada H2X 2P2 Canada
Citazione:
M.K. Tulic et al., "Small airway inflammation in asthma", RESPIR RES, 2(6), 2001, pp. 333-339

Abstract

Asthma was originally described as an inflammatory disease that predominantly involves the central airways. Pathological and physiological evidence reported during the past few years suggests that the inflammatory process extends beyond the central airways to the peripheral airways and the lung parenchyma. The small airways are capable of producing T-helper-2 cytokines, as well as chemokines, and they have recently been recognized as a predominant site of airflow obstruction in asthmatic persons. The inflammation at this distal site has been described as more severe than large airway inflammation. These findings are of great clinical significance, and highlight the need to consider the peripheral airways as a target in any therapeutic strategy for treatment of asthma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 22:58:37