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Titolo:
Kava-kava (LI 150) in the treatment of generalized anxiety disorder
Autore:
Wheatley, D;
Indirizzi:
Psychopharmacol Res Grp, London, England Psychopharmacol Res Grp London England armacol Res Grp, London, England
Titolo Testata:
PRIMARY CARE PSYCHIATRY
fascicolo: 3, volume: 7, anno: 2001,
pagine: 97 - 100
SICI:
1355-2570(200109)7:3<97:K(1ITT>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLACEBO; KAWAIN;
Keywords:
generalized anxiety disorder; Hamilton Anxiety Rating Scale; Kava-kava; side-effects;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Wheatley, D Psychopharmacol Res Grp, London, England Psychopharmacol Res Grp London England Grp, London, England
Citazione:
D. Wheatley, "Kava-kava (LI 150) in the treatment of generalized anxiety disorder", PRIM CARE P, 7(3), 2001, pp. 97-100

Abstract

The herbal extract kava-kava was used for treating 24 patents suffering from generalized anxiety disorder for a period of 4 weeks. Two dose scheduleswere compared: 120 mg once daily and 45 mg three times daily in a randomized-order, cross-over open trial. There were highly significant reductions in their mean Hamilton Anxiety Rating Scale scores (P < 0.001), irrespectiveof dose schedule, treatment order or sex of the patients. The impact of side-effects was relatively low and only one patient had to omit treatment ona three times daily dosage because of nausea. No side-effects were experienced by nine patients (37%) on three times daily dosages and by five patents (22%) on once daily dosages, but daytime drowsiness occurred in eight patients (33%) on three times daily dosages and two patients (9%) on once daily dosages. There were 13 patient preferences for once daily dosages and eight patient preferences for three times daily dosages, with no preferences in the remaining two cases. It was considered that the trial had shown kava-kava to be effective in both dose schedules, thus justifying further research with double-blind controlled studies in order to verify this.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:18:52