Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
High cervical spinal cord stimulation (CSCS) increases regional cerebral blood flow after induced subarachnoid haemorrhage in rats
Autore:
Ebel, H; Schomacker, K; Balogh, A; Volz, M; Funke, J; Schicha, H; Klug, N;
Indirizzi:
Univ Cologne, Neurochirurg Klin, Dept Neurosurg, D-50924 Cologne, Germany Univ Cologne Cologne Germany D-50924 Neurosurg, D-50924 Cologne, Germany Univ Cologne, Dept Nucl Med, D-50924 Cologne, Germany Univ Cologne Cologne Germany D-50924 Nucl Med, D-50924 Cologne, Germany Debrecen Univ Med, Dept Neurosurg, H-4012 Debrecen, Hungary Debrecen Univ Med Debrecen Hungary H-4012 surg, H-4012 Debrecen, Hungary
Titolo Testata:
MINIMALLY INVASIVE NEUROSURGERY
fascicolo: 3, volume: 44, anno: 2001,
pagine: 167 - 171
SICI:
0946-7211(200109)44:3<167:HCSCS(>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
ELECTRICAL-STIMULATION; ANIMAL-MODEL; SUBSTANCE-P; HEMORRHAGE; VASOSPASM; SPECT; ISCHEMIA; GANGLION; DISEASE; HEMODYNAMICS;
Keywords:
subarachnoid haemorrhage; spinal cord stimulation; regional cerebral blood flow; 99(m)Tc-HMPAO; cerebral vasospasm;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Ebel, H Univ Cologne, Neurochirurg Klin, Dept Neurosurg, Joseph Stelzmann Str 9, D-50924 Cologne, Germany Univ Cologne Joseph Stelzmann Str 9 Cologne Germany D-50924 rmany
Citazione:
H. Ebel et al., "High cervical spinal cord stimulation (CSCS) increases regional cerebral blood flow after induced subarachnoid haemorrhage in rats", MIN IN NEUR, 44(3), 2001, pp. 167-171

Abstract

The effects of high cervical spinal cord stimulation (cSCS) on regional cerebral blood flow (rCBF) were investigated after experimentally induced subarachnoid haemorrhage (SAH) in rats by the means of Tc-99m-HMPAO. The experiments were carried out on a total of 24 Wistar rats, divided in three groups [group I: control without SAH, group II: SAH, group III: SAH and cSCS]. Tc-99m-HMPAO was administered intravenously (groupII/group III) 48 hours after induction of SAH. In group III, Tc-99m-HMPAO was given after 3 hours ofcSCS. All animals were sacrificed 30 minutes after application on Tc-99m-HMPAO. Radioactivities were determined in blood, cerebrum and cerebellum. The ratio cerebrum/blood and cerebellum/blood was calculated to ascertain " extraction rate " in the sample differentially. The following mean values were calculated for the cerebellum/ blood ratio: Group I: 1.06, SD: 0.21; Group II 0.66, SD: 0.21; Group III: 1.00, SD: 0.37. Comparing the mean values a highly significant difference could be found between group II and III (p = 0.007) and between group I and II (p = 0.0019), respectively. Calculations of the cerebrum/blood ratio revealed similar results. After SAH cSCS enhances cerebral and cerebellar blood flow in rats. Possibly, cSCD constitutesa new therapeutic approach in the treatment of disturbed regional cerebralblood flow after SAH.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/06/19 alle ore 17:01:39