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Titolo:
Management of the pediatric liver transplant patient
Autore:
McDiarmid, SV;
Indirizzi:
Univ Calif Los Angeles, Med Ctr, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA
Titolo Testata:
LIVER TRANSPLANTATION
fascicolo: 11, volume: 7, anno: 2001, supplemento:, 1
pagine: S77 - S86
SICI:
1527-6465(200111)7:11<S77:MOTPLT>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPSTEIN-BARR-VIRUS; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE; HEPATIC-ARTERY THROMBOSIS; STEROID WITHDRAWAL; PRIMARY IMMUNOSUPPRESSION; ORGAN-TRANSPLANTATION; MYCOPHENOLATE-MOFETIL; ALLOGRAFT RECIPIENTS; NUTRITIONAL-STATUS; ENTERAL NUTRITION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
111
Recensione:
Indirizzi per estratti:
Indirizzo: McDiarmid, SV Univ Calif Los Angeles, Med Ctr, 10833 Le Conte, Los Angeles, CA 90095 USA Univ Calif Los Angeles 10833 Le Conte Los Angeles CA USA 90095
Citazione:
S.V. McDiarmid, "Management of the pediatric liver transplant patient", LIVER TRANS, 7(11), 2001, pp. S77-S86

Abstract

1. In pretransplant management, the prevention and treatment of malnutrition is essential for pediatric patients as malnutrition is associated with both increased pre- and posttransplant mortality.2. Technical complications, particularly hepatic artery thrombosis, after pediatric liver transplantation are relatively common given the small size of the majority of the recipients. Early recognition is essential to reducethe associated increased risk for both patient and graft loss.3. Immunosuppression regimens in children should aim to begin weaning of steroids within the first year after transplant because of their detrimentalimpact on growth.4. Long-term immunosuppression strategies must focus on avoiding the risksof long-term immunosuppression, particularly nephrotoxicity, neurotoxicity, de novo malignancy, and late infections.5. EBV-associated PTLD is a special problem for young pediatric liver recipients. Strategies for prevention and preemptive management are essential.6. Noncompliance in teens is a particular problem and is associated not only with graft dysfunction, but also with graft loss and patient death. Recognizing teens at risk and providing intervention strategies require a multidisciplinary approach.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 09:49:53