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Titolo:
Duration of anticoagulation for venous thromboembolism
Autore:
Kearon, C;
Indirizzi:
McMaster Univ, Hamilton, ON, Canada McMaster Univ Hamilton ON CanadaMcMaster Univ, Hamilton, ON, Canada
Titolo Testata:
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
fascicolo: 1, volume: 12, anno: 2001,
pagine: 59 - 65
SICI:
0929-5305(200109)12:1<59:DOAFVT>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEEP-VEIN THROMBOSIS; FACTOR-V-LEIDEN; PULMONARY-EMBOLISM; BLEEDING COMPLICATIONS; PROTHROMBIN GENE; INHERITED THROMBOPHILIA; FIRST EPISODE; RISK FACTOR; THERAPY; WARFARIN;
Keywords:
venous thromboembolism; deep vein thrombosis; pulmonary embolism; anticoagulant therapy; duration; warfarin;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: Kearon, C Henderson Gen Hosp, McMaster Clin, Room 401,Concess St, Hamilton, ON L8V 1C3, Canada Henderson Gen Hosp Room 401,Concess St Hamilton ON Canada L8V 1C3
Citazione:
C. Kearon, "Duration of anticoagulation for venous thromboembolism", J THROMB TH, 12(1), 2001, pp. 59-65

Abstract

The duration of oral anticoagulant therapy for venous thromboembolism (VTE) depends on the risk of recurrence if treatment is stopped and the risk ofbleeding if treatment is continued. If the risk of recurrence is low (e.g., thrombosis provoked by a major reversible risk factor such as surgery), 3months of treatment is usually adequate. If the risk of recurrence is high(unprovoked "idiopathic" VTE or associated with a non-reversible risk factor such as active cancer), 6 months or indefinite anticoagulant therapy is indicated. The presence of malignancy, an antiphospholipid antibody, and other selected thrombophilic states suggests more prolonged therapy, whereas isolated distal deep vein thrombosis, high risk of bleeding, and patient preference suggest a shorter course of treatment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 18:43:58