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Titolo:
Iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients
Autore:
Chiba, T; Kashiwagi, K; Kogure, S; Abe, K; Shibuya, T; Furuichi, M; Iijima, H; Tsukahara, S;
Indirizzi:
Yamanashi Med Univ, Dept Ophthalmol, Yamanashi 4093898, Japan Yamanashi Med Univ Yamanashi Japan 4093898 mol, Yamanashi 4093898, Japan
Titolo Testata:
JOURNAL OF GLAUCOMA
fascicolo: 5, volume: 10, anno: 2001,
pagine: 406 - 410
SICI:
1057-0829(200110)10:5<406:IPIBLO>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
OCULAR HYPERTENSION; PROSTAGLANDINS; TIMOLOL; 6-MONTH; COLOR;
Keywords:
glaucoma; iridial pigmentation; Japanese; latanoprost;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Kashiwagi, K Yamanashi Med Univ, Dept Ophthalmol, 1100 Shimokato, Yamanashi 4093898, Japan Yamanashi Med Univ 1100 Shimokato Yamanashi Japan 4093898an
Citazione:
T. Chiba et al., "Iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients", J GLAUCOMA, 10(5), 2001, pp. 406-410

Abstract

Purpose: To investigate the incidence of iridial pigmentation induced by latanoprost ophthalmic solution in Japanese glaucoma patients by a prospective and observer-masked study. Patients and Methods: Sixty-nine eyes of 69 glaucoma patients were included. Patients who had undergone intraocular surgery, laser trabeculoplasty, and laser iridotomy within 12 months before enrollment, and patients with history of uveitis and any changes in antiglaucoma drugs within 6 months before enrollment were excluded. Iridial photographs were taken by one examinerunder the same conditions at 1, 3, and 6 months after the initiation of latanoprost treatment. Three glaucoma specialists, masked of patient information, independently assessed the iridial pigmentation. Cases with iridial pigmentation diagnosed by three specialists were categorized as showing a definite increase in iridial pigmentation. Results: A definite increase in iridial pigmentation occurred in 3.5%, 9.7%, and 35.0% of eyes within 1, 3, and 6 months of treatment, respectively. Age, gender, or concomitantly used eyedrops did not significantly influencethe incidence of iridial pigmentation within 6 months of instillation. A reduction of intraocular pressure by latanoprost did not differ significantly between patients with and without iridial pigmentation. Conclusion: The incidence of iridial pigmentation by latanoprost ophthalmic solution in Japanese patients was higher than previously reported values in pigmented races.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/05/20 alle ore 14:50:38