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Titolo:
"Host factors" - evolution of concepts of individual sensitivity and susceptibility
Autore:
Hoffmann, W; Oberheitmann, B; Frentzel-Beyme, R;
Indirizzi:
Bremen Inst Prevent Res Social Med & Epidemiol, D-28359 Bremen, Germany Bremen Inst Prevent Res Social Med & Epidemiol Bremen Germany D-28359 ny Univ Bremen, UFT, Ctr Environm Res & Technol, D-28359 Bremen, Germany UnivBremen Bremen Germany D-28359 es & Technol, D-28359 Bremen, Germany
Titolo Testata:
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
fascicolo: 1, volume: 204, anno: 2001,
pagine: 5 - 15
SICI:
1438-4639(200110)204:1<5:"F-EOC>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUTATHIONE-S-TRANSFERASE; NORMAL-TISSUE RADIOSENSITIVITY; CARCINOGEN-HEMOGLOBIN ADDUCTS; NIJMEGEN BREAKAGE SYNDROME; HUMAN SKIN FIBROBLASTS; DNA-REPAIR CAPACITY; LUNG-CANCER RISK; BREAST-CANCER; CHROMOSOMAL RADIOSENSITIVITY; ATAXIA-TELANGIECTASIA;
Keywords:
host factors; individual sensitivity; individual susceptibility; hereditary susceptibility; acquired susceptibility; prevention;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
84
Recensione:
Indirizzi per estratti:
Indirizzo: Hoffmann, W Bremen Inst Prevent Res Social Med & Epidemiol, Linzer Str 8-10, D-28359 Bremen, Germany Bremen Inst Prevent Res Social Med & Epidemiol Linzer Str 8-10 Bremen Germany D-28359
Citazione:
W. Hoffmann et al., ""Host factors" - evolution of concepts of individual sensitivity and susceptibility", INT J HYG E, 204(1), 2001, pp. 5-15

Abstract

The detection of a rapidly increasing number of genetic polymorphisms in xenogen-metabolizing enzymes, of hereditary as well as acquired individual differences in DNA repair, and of the close associations between central nervous structures, the endocrine, and the immune system provides a challenge to develop an evidence-based, comprehensive model of susceptibility. Reviewing the evolution of respective approaches from 400 B.C. until today, this article proposes a conceptional framework that integrates the diverse, and sometimes puzzling contributions from all different fields of life science.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 19:26:49