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Titolo:
Second transplantation with CD34(+) blood cells from an HLA-mismatched related donor after engraftment failure of transplanted cord blood cells
Autore:
Ohta, H; Kim, JY; Sawada, A; Tokimasa, S; Fujisaki, H; Matsuda, Y; Osugi, Y; Hara, J;
Indirizzi:
Osaka Univ, Grad Sch Med, Dept Dev Med Pediat, Suita, Osaka 5650871, JapanOsaka Univ Suita Osaka Japan 5650871 Pediat, Suita, Osaka 5650871, Japan
Titolo Testata:
INTERNATIONAL JOURNAL OF HEMATOLOGY
fascicolo: 3, volume: 74, anno: 2001,
pagine: 338 - 341
SICI:
0925-5710(200110)74:3<338:STWCBC>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW TRANSPLANTATION; ALLOGENEIC TRANSPLANTATION; PERIPHERAL-BLOOD; ACUTE-LEUKEMIA; MALIGNANCIES; EXPERIENCE; CHILDREN;
Keywords:
second transplantation; CD34(+) blood cells; engraftment failure; cord blood transplantation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Ohta, H Osaka Univ, Grad Sch Med, Dept Dev Med Pediat, D-5,2-2 Yamadaoka, Suita, Osaka 5650871, Japan Osaka Univ D-5,2-2 Yamadaoka Suita Osaka Japan 5650871 0871, Japan
Citazione:
H. Ohta et al., "Second transplantation with CD34(+) blood cells from an HLA-mismatched related donor after engraftment failure of transplanted cord blood cells", INT J HEMAT, 74(3), 2001, pp. 338-341

Abstract

Unrelated cord blood transplantation (CBT) has been worldwide for bone marrow reconstitution. CBT is associated with a high frequency of engraftment failure and rejection due to a small dose of graft cells. In cases of engraftment failure or rejection following unrelated CBT retransplantation from the original donors is impossible. We report a successful transplantation with CD34(+) blood cells selected from a 2-loci HLA-mismatched mother to a child with acute monocytic leukemia after engraftment failure of the primaryCBT. Selected CD34(+) blood cell transplantation is a useful approach for retransplantation in the setting of engraftment failure. (C) 2001 The Japanese Society of Hematology.

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Documento generato il 01/06/20 alle ore 02:35:52