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Titolo:
Polycystic ovary syndrome and cancer
Autore:
Balen, A;
Indirizzi:
Gen Infirm, Dept Reprod Med, Leeds LS2 9NS, W Yorkshire, England Gen Infirm Leeds W Yorkshire England LS2 9NS S2 9NS, W Yorkshire, England
Titolo Testata:
HUMAN REPRODUCTION UPDATE
fascicolo: 6, volume: 7, anno: 2001,
pagine: 522 - 525
SICI:
1355-4786(200111/12)7:6<522:POSAC>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
STEIN-LEVENTHAL SYNDROME; ENDOMETRIAL ADENOCARCINOMA; INFERTILE WOMEN; YOUNG-WOMEN; RISK FACTOR; EPIDEMIOLOGY; PATHOGENESIS; CARCINOMA; NEOPLASIA;
Keywords:
breast cancer; endometrial cancer; ovarian cancer; polycystic ovaries;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Balen, A Gen Infirm, Dept Reprod Med, Leeds LS2 9NS, W Yorkshire, England Gen Infirm Leeds W Yorkshire England LS2 9NS Yorkshire, England
Citazione:
A. Balen, "Polycystic ovary syndrome and cancer", HUM REP UPD, 7(6), 2001, pp. 522-525

Abstract

The polycystic ovary syndrome (PCOS) is the most common endocrine disturbance affecting women, but disagreements in diagnostic criteria make it difficult to compare epidemiological studies on long-term health risks such as cancer. The association between PCOS and endometrial adenocarcinoma has beenreported for many years. Although the degree of risk has not been clearly defined, it is generally accepted that for women with PCOS who experience symptoms of amenorrhoea or oligomenorrhoea, the induction of artificial withdrawal bleeds to prevent endometrial hyperplasia is prudent management. Studies examining the relationship between PCOS and breast carcinoma have not always identified a significantly increased risk, although one recent studyexamined the standardized mortality rate (SMR) calculated for patients with PCOS compared with the normal population and found that the SMR for all neoplasms was 0.91 (95% CI 0.60-1.32) and for breast cancer 1.48 (95% CI 0.79-2.54). Few studies have addressed the possibility of an association between polycystic ovaries and ovarian cancer, and the results are conflicting and generally reassuring.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 05:34:29