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Titolo:
Ongoing clinical trials in systemic hypertension
Autore:
Mann, J; Oddou, P;
Indirizzi:
Speedel Grp, CH-4051 Basel, Switzerland Speedel Grp Basel Switzerland CH-4051 el Grp, CH-4051 Basel, Switzerland
Titolo Testata:
EXPERT OPINION ON INVESTIGATIONAL DRUGS
fascicolo: 11, volume: 10, anno: 2001,
pagine: 2031 - 2037
SICI:
1354-3784(200111)10:11<2031:OCTISH>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
RANDOMIZED TRIAL; CARDIOVASCULAR MORBIDITY; SYSTOLIC HYPERTENSION; RATIONALE; DESIGN; MANAGEMENT; GUIDELINES; MORTALITY; BLOCKERS; STROKE;
Keywords:
angiotensin converting enzyme inhibitors; angiotensin receptor blockers; calcium channel blockers; cardiovascular mortality; clinical trials; hypertension;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Mann, J Speedel Grp, Hirschgaesslein 11, CH-4051 Basel, Switzerland Speedel Grp Hirschgaesslein 11 Basel Switzerland CH-4051 tzerland
Citazione:
J. Mann e P. Oddou, "Ongoing clinical trials in systemic hypertension", EXPERT OP I, 10(11), 2001, pp. 2031-2037

Abstract

Hypertension was identified as a cardiovascular risk factor in the late fifties and still remains a public health issue. The number of patients treated reaches only half of those diagnosed and, of those treated, half fail toreach target blood pressure. Furthermore, the number of anti hypertensive drugs reaching the market has increased exponentially in the last few years, however, the impact on treatment and on attaining target blood pressure levels remains to be seen. The high percentage of treated patients who do not reach target blood pressure, combined with the high number of patients requiring more than one anti hypertensive drug, have triggered a series of long-term morbidity and mortality trials comparing different therapeutic approaches ('new' pharmacological classes vs. 'old' pharmacological classes). These are described in this paper.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 15:45:25